BIOPEP-UWM: Report

ID 2679
Name Erythropoietin mimetic
sequence
GGDYHCRMGPLTWVCKPLGG
Function:
Stimulates red blood cells creation
 
Number of residues
20
Activity code
sti
Activity :
stimulating
Chemical mass 2147.4997 Monoisotopic mass 2145.9879
EC50 :
0.00 µM


Bibliographic data:
Authors
Wrighton N. C., Farrell F. X., Chang R., Kashyap A. K., Barbone F. P., Mulcahy L. S., Johnson D. L., Barrett R. W., Jolliffe L. K., Dower W. J.
Title
Small peptides as potent mimetics of the protein hormone erythropoietin. Science, 273, 458-463, 1996
Year Source
1996 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: [H][C@@](CS)(NC(=O)[C@]([H])(Cc1cnc[nH]1)NC(=O)[C@]([H])(Cc1ccc(O)cc1)NC(=O)[C@]([H])(CC(O)=O)NC(=O)CNC(=O)CN)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CCSC)C(=O)NCC(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])(Cc1c[nH]c2ccccc12)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCCN)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(=O)NCC(O)=O

InChI=1S/C94H143N27O25S3/c1-48(2)32-61(80(133)104-41-72(125)103-44-76(130)131)113-90(143)70-21-15-30-121(70)93(146)60(18-11-12-27-95)110-88(141)68(46-148)117-91(144)77(50(5)6)118-86(139)64(35-53-39-101-57-17-10-9-16-56(53)57)115-92(145)78(51(7)122)119-85(138)62(33-49(3)4)114-89(142)69-20-14-29-120(69)74(127)43-105-79(132)59(26-31-149-8)109-81(134)58(19-13-28-100-94(97)98)108-87(140)67(45-147)116-83(136)65(36-54-40-99-47-106-54)112-82(135)63(34-52-22-24-55(123)25-23-52)111-84(137)66(37-75(128)129)107-73(126)42-102-71(124)38-96/h9-10,16-17,22-25,39-40,47-51,58-70,77-78,101,122-123,147-148H,11-15,18-21,26-38,41-46,95-96H2,1-8H3,(H,99,106)(H,102,124)(H,103,125)(H,104,133)(H,105,132)(H,107,126)(H,108,140)(H,109,134)(H,110,141)(H,111,137)(H,112,135)(H,113,143)(H,114,142)(H,115,145)(H,116,136)(H,117,144)(H,118,139)(H,119,138)(H,128,129)(H,130,131)(H4,97,98,100)/t51-,58+,59+,60+,61+,62+,63+,64+,65+,66+,67+,68+,69+,70+,77+,78+/m1/s1

InChIKey: QHLHSMCQKAOHKX-BPIFFIGMSA-N


Database reference: