BIOPEP-UWM: Report

ID 2682
Name Erythropoietin receptor agonist
sequence
DLEGCRLGWVGHCNVWGGDEYTKRTSHSVPPSHKSKLL
Function:
Stimulates red blood cells creation
 
Number of residues
38
Activity code
sti
Activity :
stimulating
Chemical mass 4250.7240 Monoisotopic mass 4248.0681
EC50 :
0.00 µM


Bibliographic data:
Authors
McConnell S. J., Dinh T., Le M-H., Brown S. J., Becherer K., Blumeyer K., Kautze
Title
Isolation of erythropoietin receptor agonist peptides using evolved phage libraries. Biol. Chem., 379, 1279-1286 (1998)
Year Source
1998 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: [H][C@](N)(CC(O)=O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)NCC(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(=O)N[C@@]([H])(Cc1c[nH]c2ccccc12)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(Cc1cnc[nH]1)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(Cc1c[nH]c2ccccc12)C(=O)NCC(=O)NCC(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(Cc1cnc[nH]1)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(C(C)C)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(Cc1cnc[nH]1)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(O)=O

InChI=1S/C186H286N56O55S2/c1-89(2)57-117(223-158(270)113(38-27-53-199-185(192)193)218-175(287)133(84-298)214-142(255)78-205-153(265)115(46-48-143(256)257)219-162(274)118(58-90(3)4)222-152(264)107(190)67-145(260)261)154(266)206-77-140(253)211-122(63-100-71-202-109-34-20-18-32-106(100)109)169(281)236-147(93(9)10)178(290)207-79-141(254)212-123(64-101-72-196-86-208-101)164(276)235-134(85-299)176(288)228-126(68-137(191)250)170(282)237-148(94(11)12)179(291)229-121(62-99-70-201-108-33-19-17-31-105(99)108)155(267)204-75-138(251)203-76-139(252)213-127(69-146(262)263)167(279)220-116(47-49-144(258)259)160(272)225-120(61-98-42-44-104(249)45-43-98)168(280)240-150(96(15)247)180(292)221-112(37-23-26-52-189)156(268)215-114(39-28-54-200-186(194)195)161(273)239-151(97(16)248)181(293)234-131(82-245)173(285)227-125(66-103-74-198-88-210-103)166(278)232-132(83-246)174(286)238-149(95(13)14)183(295)242-56-30-41-136(242)182(294)241-55-29-40-135(241)177(289)233-130(81-244)172(284)226-124(65-102-73-197-87-209-102)165(277)216-111(36-22-25-51-188)159(271)231-129(80-243)171(283)217-110(35-21-24-50-187)157(269)224-119(59-91(5)6)163(275)230-128(184(296)297)60-92(7)8/h17-20,31-34,42-45,70-74,86-97,107,110-136,147-151,201-202,243-249,298-299H,21-30,35-41,46-69,75-85,187-190H2,1-16H3,(H2,191,250)(H,196,208)(H,197,209)(H,198,210)(H,203,251)(H,204,267)(H,205,265)(H,206,266)(H,207,290)(H,211,253)(H,212,254)(H,213,252)(H,214,255)(H,215,268)(H,216,277)(H,217,283)(H,218,287)(H,219,274)(H,220,279)(H,221,292)(H,222,264)(H,223,270)(H,224,269)(H,225,272)(H,226,284)(H,227,285)(H,228,288)(H,229,291)(H,230,275)(H,231,271)(H,232,278)(H,233,289)(H,234,293)(H,235,276)(H,236,281)(H,237,282)(H,238,286)(H,239,273)(H,240,280)(H,256,257)(H,258,259)(H,260,261)(H,262,263)(H,296,297)(H4,192,193,199)(H4,194,195,200)/t96-,97-,107+,110+,111+,112+,113+,114+,115+,116+,117+,118+,119+,120+,121+,122+,123+,124+,125+,126+,127+,128+,129+,130+,131+,132+,133+,134+,135+,136+,147+,148+,149+,150+,151+/m1/s1

InChIKey: FPSITAZLLKFEFR-OOUGEXORSA-N


Database reference: