BIOPEP-UWM: Report

ID 2686
Name
sequence
GNADGPTLRQWLEGRRPKN
Function:
stimulating blood platelet production
 
Number of residues
19
Activity code
sti
Activity :
stimulating
Chemical mass 2165.3658 Monoisotopic mass 2164.1217
EC50 :
0.00 µM


Bibliographic data:
Authors
Cwirla S. E., Balasubramanian P., Duffin D. J., Wagstrom C. R., Gates C. M., Singer S. C., Davis A. M., Tansik R. L., Mattheakis L. C., Boytos C. M.,
Title
Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine. Science, 276, 1696-1699, 1997
Year Source
1997 Journal


Additional information:

BIOPEP-UWM database of bioactive peptides


SMILES: [H][C@@](C)(NC(=O)[C@]([H])(CC(N)=O)NC(=O)CN)C(=O)N[C@@]([H])(CC(O)=O)C(=O)NCC(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(Cc1c[nH]c2ccccc12)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)NCC(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(N)=O)C(O)=O

InChI=1S/C92H149N33O28/c1-44(2)34-57(82(145)114-54(25-27-71(133)134)75(138)108-42-69(131)111-51(19-11-29-104-90(98)99)77(140)117-56(21-13-31-106-92(102)103)88(151)125-33-15-23-64(125)85(148)116-52(18-9-10-28-93)79(142)122-62(89(152)153)38-67(97)129)119-84(147)59(36-48-41-107-50-17-8-7-16-49(48)50)120-80(143)55(24-26-65(95)127)115-78(141)53(20-12-30-105-91(100)101)113-83(146)58(35-45(3)4)121-87(150)73(47(6)126)123-86(149)63-22-14-32-124(63)70(132)43-109-76(139)61(39-72(135)136)118-74(137)46(5)110-81(144)60(37-66(96)128)112-68(130)40-94/h7-8,16-17,41,44-47,51-64,73,107,126H,9-15,18-40,42-43,93-94H2,1-6H3,(H2,95,127)(H2,96,128)(H2,97,129)(H,108,138)(H,109,139)(H,110,144)(H,111,131)(H,112,130)(H,113,146)(H,114,145)(H,115,141)(H,116,148)(H,117,140)(H,118,137)(H,119,147)(H,120,143)(H,121,150)(H,122,142)(H,123,149)(H,133,134)(H,135,136)(H,152,153)(H4,98,99,104)(H4,100,101,105)(H4,102,103,106)/t46-,47+,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,73-/m0/s1

InChIKey: AXKCOOBXYGPVAC-FXMDRCMLSA-N


Database reference: