BIOPEP-UWM: Report

ID 2703
Name Antibacterial peptide
sequence
CIGNGGRCNENVGPPYCCSGFCCLRQPNQGYGVCRNA
Function:
Antibacterial peptide
 
Number of residues
37
Activity code
ab
Activity :
antibacterial
Chemical mass 3911.4139 Monoisotopic mass 3908.6250
EC50 :
0.00 µM


Bibliographic data:
Authors
Saberwal G., Nagaraj R.
Title
Cell-lytic and antibacterial peptides that act by perturbing the barrier function of membranes: facets of their conformational features, structure-function correlations and membrane-perturbing abilities. BBA, 1197, 109-131, 1994
Year Source
1994 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: [H][C@](N)(CS)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)NCC(=O)N[C@@]([H])(CC(N)=O)C(=O)NCC(=O)NCC(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CO)C(=O)NCC(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)NCC(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(C)C(O)=O

InChI=1S/C158H245N53O50S7/c1-10-75(8)125(208-126(231)82(159)65-262)151(256)181-61-119(226)187-93(52-110(162)217)129(234)177-57-115(222)176-58-116(223)184-83(22-14-42-173-156(167)168)131(236)200-99(66-263)144(249)196-95(54-112(164)219)139(244)191-87(38-41-122(229)230)134(239)195-97(56-114(166)221)141(246)207-123(73(4)5)150(255)182-63-121(228)209-45-19-27-107(209)154(259)211-47-18-26-106(211)149(254)197-92(51-79-30-34-81(214)35-31-79)138(243)202-103(70-267)147(252)204-101(68-265)145(250)199-98(64-212)130(235)180-60-118(225)186-91(49-77-20-12-11-13-21-77)137(242)201-102(69-266)146(251)203-100(67-264)143(248)193-89(48-72(2)3)136(241)188-84(23-15-43-174-157(169)170)132(237)192-88(37-40-109(161)216)153(258)210-46-17-25-105(210)148(253)198-96(55-113(165)220)140(245)190-86(36-39-108(160)215)127(232)178-59-117(224)185-90(50-78-28-32-80(213)33-29-78)128(233)179-62-120(227)206-124(74(6)7)152(257)205-104(71-268)142(247)189-85(24-16-44-175-158(171)172)133(238)194-94(53-111(163)218)135(240)183-76(9)155(260)261/h11-13,20-21,28-35,72-76,82-107,123-125,212-214,262-268H,10,14-19,22-27,36-71,159H2,1-9H3,(H2,160,215)(H2,161,216)(H2,162,217)(H2,163,218)(H2,164,219)(H2,165,220)(H2,166,221)(H,176,222)(H,177,234)(H,178,232)(H,179,233)(H,180,235)(H,181,256)(H,182,255)(H,183,240)(H,184,223)(H,185,224)(H,186,225)(H,187,226)(H,188,241)(H,189,247)(H,190,245)(H,191,244)(H,192,237)(H,193,248)(H,194,238)(H,195,239)(H,196,249)(H,197,254)(H,198,253)(H,199,250)(H,200,236)(H,201,242)(H,202,243)(H,203,251)(H,204,252)(H,205,257)(H,206,227)(H,207,246)(H,208,231)(H,229,230)(H,260,261)(H4,167,168,173)(H4,169,170,174)(H4,171,172,175)/t75-,76-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,123-,124-,125-/m0/s1


InChIKey=MVJPRDSMVRPAJY-NYXAYPJDSA-N


Active against G(+) and G(-) bacteria


Database reference: