BIOPEP-UWM: Report
| ID | 2731 |
| Name | renin inhibitor |
| sequence |
| Function: | |||
| Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID A01.007) | |||
| Number of residues | 9 |
Activity code | ren |
| Activity : | renin inhibitor |
|||
| Chemical mass | 1190.3471 | Monoisotopic mass | 1189.5692 | |
| EC50 : | 0.00 µM |
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| Bibliographic data: | |
| Authors | |
| Ondetti M. A., Cushman D. W. | |
| Title | |
| Enzymes of the renin-angiotensin system and their inhibitors. Annu. Rev. Biochem., 51, 283-308 (1982) | |
| Year | Source |
| 1982 | Journal |
| Additional information: |
| BIOPEP-UWM database of bioactive peptides SMILES: [H][C@@](CC1=CN=CN1)(NC(=O)[C@]([H])(Cc1ccccc1)NC(=O)[C@]1([H])CCCN1C(=O)[C@]([H])(CC1=CN=CN1)NC(=O)[C@]1([H])CCCN1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(O)=O InChI=1S/C63H75N13O11/c1-38(2)54(61(84)74-52(63(86)87)31-42-22-24-45(77)25-23-42)75-59(82)49(30-41-18-10-5-11-19-41)70-56(79)47(28-39-14-6-3-7-15-39)69-58(81)50(32-43-34-64-36-67-43)71-57(80)48(29-40-16-8-4-9-17-40)72-60(83)53-21-13-27-76(53)62(85)51(33-44-35-65-37-68-44)73-55(78)46-20-12-26-66-46/h3-11,14-19,22-25,34-38,46-54,66,77H,12-13,20-21,26-33H2,1-2H3,(H,64,67)(H,65,68)(H,69,81)(H,70,79)(H,71,80)(H,72,83)(H,73,78)(H,74,84)(H,75,82)(H,86,87)/t46-,47-,48-,49-,50-,51-,52-,53-,54-/m0/s1 InChIKey=LZANPSMBIHLZRC-AIZAZPTRSA-N Information concerning Renin is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: A01.007 |
| Database reference: |