BIOPEP-UWM: Report

ID 2761
Name rat defensin murine cryptidin
sequence
VCYCRSRGCKGRERMNGTCRKGHLLYTLCCR
Function:
 
Number of residues
31
Activity code
ab
Activity :
antibacterial
Chemical mass 3624.3219 Monoisotopic mass 3621.7025
EC50 :
0.00 µM


Bibliographic data:
Authors
Saberwal G., Nagaraj R.
Title
Cell-lytic and antibacterial peptides that act by perturbing the barrier function of membranes: facets of their conformational features, structure-function correlations and membrane-perturbing abilities. BBA, 1197, 109-131, 1994
Year Source
1994 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(C(C)C)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)NCC(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCCN)C(=O)NCC(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CC(N)=O)C(=O)NCC(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CCCCN)C(=O)NCC(=O)N[C@@]([H])(CC1=CN=CN1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCNC(N)=N)C(O)=O

InChI=1S/C146H248N54O40S7/c1-70(2)50-91(124(223)187-92(51-71(3)4)125(224)189-95(54-77-32-36-80(205)37-33-77)129(228)200-113(75(10)203)139(238)192-93(52-72(5)6)126(225)194-102(66-244)136(235)196-101(65-243)134(233)186-90(140(239)240)29-21-48-169-146(161)162)188-128(227)96(55-78-57-163-69-174-78)176-107(208)59-171-114(213)81(22-12-14-41-147)178-119(218)86(27-19-46-167-144(157)158)182-133(232)104(68-246)198-138(237)112(74(9)202)199-109(210)61-173-117(216)97(56-105(149)206)191-123(222)89(40-49-247-11)185-120(219)85(26-18-45-166-143(155)156)181-122(221)88(38-39-110(211)212)184-118(217)84(25-17-44-165-142(153)154)175-106(207)58-170-115(214)82(23-13-15-42-148)180-131(230)99(63-241)177-108(209)60-172-116(215)83(24-16-43-164-141(151)152)179-130(229)98(62-201)193-121(220)87(28-20-47-168-145(159)160)183-132(231)100(64-242)195-127(226)94(53-76-30-34-79(204)35-31-76)190-135(234)103(67-245)197-137(236)111(150)73(7)8/h30-37,57,69-75,81-104,111-113,201-205,241-246H,12-29,38-56,58-68,147-148,150H2,1-11H3,(H2,149,206)(H,163,174)(H,170,214)(H,171,213)(H,172,215)(H,173,216)(H,175,207)(H,176,208)(H,177,209)(H,178,218)(H,179,229)(H,180,230)(H,181,221)(H,182,232)(H,183,231)(H,184,217)(H,185,219)(H,186,233)(H,187,223)(H,188,227)(H,189,224)(H,190,234)(H,191,222)(H,192,238)(H,193,220)(H,194,225)(H,195,226)(H,196,235)(H,197,236)(H,198,237)(H,199,210)(H,200,228)(H,211,212)(H,239,240)(H4,151,152,164)(H4,153,154,165)(H4,155,156,166)(H4,157,158,167)(H4,159,160,168)(H4,161,162,169)/t74-,75-,81+,82+,83+,84+,85+,86+,87+,88+,89+,90+,91+,92+,93+,94+,95+,96+,97+,98+,99+,100+,101+,102+,103+,104+,111+,112+,113+/m1/s1

InChIKey=HJTHVHGSKKDJQR-NKFGJLOMSA-N



Active agaist G(+), G(-) bacteria and fungi.


Database reference: