BIOPEP-UWM: Report

ID 2772
Name protease HIV1 inhibitor
sequence
LLEYSI

Function:
Inhibitor of HIV-1 retropepsin (EC 3.4.23.16) (MEROPS ID: A02.001)
 
Number of residues
6
Activity code
avi
Activity :
antiviral
Chemical mass 736.8505 Monoisotopic mass 736.3993
EC50 :
0.00 µM



Bibliographic data:
Authors
Lee T. G., Maruyama S.
Title
Isolation of HIV-1 protease-inhibiting peptide from thermolysin hydrolysate of oyster proteins. Biochem. Biophys. Res. Commun., 253, 604-608, 1998
Year Source
1998 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])([C@@H](C)CC)C(O)=O

InChI=1S/C35H56N6O11/c1-7-20(6)29(35(51)52)41-34(50)27(17-42)40-33(49)26(16-21-8-10-22(43)11-9-21)39-31(47)24(12-13-28(44)45)37-32(48)25(15-19(4)5)38-30(46)23(36)14-18(2)3/h8-11,18-20,23-27,29,42-43H,7,12-17,36H2,1-6H3,(H,37,48)(H,38,46)(H,39,47)(H,40,49)(H,41,50)(H,44,45)(H,51,52)/t20-,23-,24-,25-,26-,27-,29-/m0/s1

InChIKey=RTYCKUDTBYMRIE-AAYIBTABSA-N



Database reference:
ChemSpider: ID 7986367

HIPdb: ID HIP1120

PubChem: CID 9810612

SATPdb: ID satpdb25270