BIOPEP-UWM: Report

ID 2801
Name Peptide T
sequence
ASTTTNYT

Function:
Inhibiting HIV receptor binding
 
Number of residues
8
Activity code
avi
Activity :
antiviral
Chemical mass 857.8597 Monoisotopic mass 857.3753
EC50 :
0.00 µM



Bibliographic data:
Authors
Pert C. B., Hill J. M., Ruff M. R., Berman R. M., Robey W. G., Arthur L. O., Ruscetti F. W., Farrar W. L.
Title
Octapeptides deduced from the neuropeptide receptor-like pattern of antigen T4 in brain potently inhibit human immunodeficiency virus receptor binding and T-cells infectivity. Proc. Natl Acad. Sci. USA, 83, 9254-9258, 1986
Year Source
1986 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES:
[H][C@@](C)(N)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])([C@@H](C)O)C(O)=O

InChI=1S/C35H55N9O16/c1-13(36)28(52)40-22(12-45)31(55)41-25(15(3)47)33(57)43-26(16(4)48)34(58)42-24(14(2)46)32(56)39-21(11-23(37)51)29(53)38-20(10-18-6-8-19(50)9-7-18)30(54)44-27(17(5)49)35(59)60/h6-9,13-17,20-22,24-27,45-50H,10-12,36H2,1-5H3,(H2,37,51)(H,38,53)(H,39,56)(H,40,52)(H,41,55)(H,42,58)(H,43,57)(H,44,54)(H,59,60)/t13-,14+,15+,16+,17+,20-,21-,22-,24-,25-,26-,27-/m0/s1

InChIKey=IWHCAJPPWOMXNW-LYKMMFCUSA-N


Inhibits HIV receptor binding T-cells.



Database reference:
ACToR: ID 106362-32-7

BRENDA: Ligand Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr

ChEMBL: ID CHEMBL180971

ChemIDplus: ID 106362327

ChemSpider: ID 66081

FDA UNII: ID 05DYM3ZS1X

HIPdb: ID HIP1064

J-GLOBAL: ID 200907094112459337

NIAID: ID 000530

Nikkaji: ID J501.338K

PubChem: CID 73352

SATPdb: ID satpdb24052

SureChEMBL: ID SCHEMBL5813760

ZINC: ID ZINC000169345692