BIOPEP-UWM: Report

ID 2803
Name PEP inhibitor
sequence
LPPPVH

Function:
Inhibitor of prolyl oligopeptidase (EC 3.4.21.26) (MEROPS ID: S09.001)
 
Number of residues
6
Activity code
am
Activity :
antiamnestic
Chemical mass 658.7868 Monoisotopic mass 658.3791
EC50 :
400.00 µM



Bibliographic data:
Authors
Maruyama S., Miyoshi S., Osa T., Tanaka H.
Title
Prolyl endopeptidase inhibitory activity of peptides in the repeated sequence of various proline-rich proteins. J. Ferment. Bioeng.,74(3), 145-148, 1992
Year Source
1992 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES:
[H][C@](N)(CC(C)C)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(Cc1cnc[nH]1)C(O)=O

InChI=1S/C32H50N8O7/c1-18(2)14-21(33)29(43)39-12-6-9-24(39)31(45)40-13-7-10-25(40)30(44)38-11-5-8-23(38)27(41)37-26(19(3)4)28(42)36-22(32(46)47)15-20-16-34-17-35-20/h16-19,21-26H,5-15,33H2,1-4H3,(H,34,35)(H,36,42)(H,37,41)(H,46,47)/t21-,22-,23-,24-,25-,26-/m0/s1

InChIKey=UJOYOAZXQXXPNK-FRSCJGFNSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database



Database reference:
AHTPDB: ID 5762

BioPepDB: ID biopep00853

SATPdb: ID satpdb23267