BIOPEP-UWM: Report

ID 2806
Name PEP inhibitor
sequence
HLPPPV

Function:
Inhibitor of prolyl oligopeptidase (EC 3.4.21.26) (MEROPS ID: S09.001)
 
Number of residues
6
Activity code
am
Activity :
antiamnestic
Chemical mass 658.7868 Monoisotopic mass 658.3791
EC50 :
400.00 µM



Bibliographic data:
Authors
Maruyama S., Miyoshi S., Osa T., Tanaka H.
Title
Prolyl endopeptidase inhibitory activity of peptides in the repeated sequence of various proline-rich proteins. J. Ferm. Bioeng.,74(3), 145-148, 1992
Year Source
1992 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES:
[H][C@@](C(N[C@](C(N1[C@@](C(N2[C@@](C(N3[C@@](C(N[C@](C(=O)O)(C(C)C)[H])=O)([H])CCC3)=O)([H])CCC2)=O)([H])CCC1)=O)(CC(C)C)[H])=O)(Cc1[nH]cnc1)N

InChI=1S/C32H50N8O7/c1-18(2)14-22(36-27(41)21(33)15-20-16-34-17-35-20)29(43)39-12-6-9-24(39)31(45)40-13-7-10-25(40)30(44)38-11-5-8-23(38)28(42)37-26(19(3)4)32(46)47/h16-19,21-26H,5-15,33H2,1-4H3,(H,34,35)(H,36,41)(H,37,42)(H,46,47)/t21-,22-,23-,24-,25-,26-/m0/s1

InChIKey: MXOJIRCLJBFUPT-FRSCJGFNSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database



Database reference:
AHTPDB: ID 5761

PeptideDB: ID biopep00463

SATPdb: ID satpdb17824