BIOPEP-UWM: Report

ID 2813
Name PEP inhibitor
sequence
GVQVETISPGDGR

Function:
Inhibitor of prolyl oligopeptidase (EC 3.4.21.26) (MEROPS ID: S09.001)
 
Number of residues
13
Activity code
am
Activity :
antiamnestic
Chemical mass 1314.3980 Monoisotopic mass 1313.6554
EC50 :
0.00 µM



Bibliographic data:
Authors
Ohmori T., Nakagami T., Tanaka H., Maruyama S.
Title
Isolation of prolyl endopeptidase-inhibiting peptide from bovine brain. Biochem. Biophys. Res. Commun. 202 (2), 809-815, 1994
Year Source
1994 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES:
[H][C@@](CO)(NC(=O)[C@@]([H])(NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CCC(O)=O)NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CCC(N)=O)NC(=O)[C@@]([H])(NC(=O)CN)C(C)C)C(C)C)[C@@H](C)O)[C@@H](C)CC)C(=O)N1CCC[C@@]1([H])C(=O)NCC(=O)N[C@@]([H])(CC(O)=O)C(=O)NCC(=O)N[C@@]([H])(CCCNC(N)=N)C(O)=O

InChI=1S/C54H91N17O21/c1-8-26(6)42(50(88)66-32(23-72)52(90)71-18-10-12-33(71)47(85)61-22-37(77)63-31(19-39(80)81)44(82)60-21-36(76)62-30(53(91)92)11-9-17-59-54(57)58)69-51(89)43(27(7)73)70-46(84)29(14-16-38(78)79)65-49(87)41(25(4)5)68-45(83)28(13-15-34(56)74)64-48(86)40(24(2)3)67-35(75)20-55/h24-33,40-43,72-73H,8-23,55H2,1-7H3,(H2,56,74)(H,60,82)(H,61,85)(H,62,76)(H,63,77)(H,64,86)(H,65,87)(H,66,88)(H,67,75)(H,68,83)(H,69,89)(H,70,84)(H,78,79)(H,80,81)(H,91,92)(H4,57,58,59)/t26-,27+,28-,29-,30-,31-,32-,33-,40-,41-,42-,43-/m0/s1

InChIKey=WXRYADPMNYBLME-VSELNXASSA-N



Database reference: