BIOPEP-UWM: Report

ID 2815
Name PEP inhibitor
sequence
MTPPPLPARVDFSLAGALN
Function:
Inhibitor of prolyl oligopeptidase (EC 3.4.21.26) (MEROPS ID: S09.001)
 
Number of residues
19
Activity code
am
Activity :
antiamnestic
Chemical mass 1967.2872 Monoisotopic mass 1966.0313
EC50 :
0.00 µM


Bibliographic data:
Authors
Maruyama S., Ohmori T., Nakagami T.
Title
Prolylendopeptidase inhibitory activity of a glial fibrillary acidic protein fragment and other proline-rich peptides. Biosci. Biotech. Biochem. 60 (2), 358-359, 1996
Year Source
1996 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES:
[H][C@](N)(CCSC)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CC(C)C)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)NCC(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(N)=O)C(O)=O

InChI=1S/C89H143N23O25S/c1-44(2)36-55(76(124)97-48(9)71(119)95-42-67(116)96-49(10)72(120)100-56(37-45(3)4)77(125)105-60(88(136)137)40-66(91)115)101-80(128)61(43-113)106-78(126)57(39-52-22-15-14-16-23-52)102-79(127)58(41-68(117)118)103-83(131)69(47(7)8)107-75(123)54(24-17-30-94-89(92)93)99-73(121)50(11)98-81(129)62-25-18-31-109(62)84(132)59(38-46(5)6)104-82(130)63-26-19-32-110(63)85(133)64-27-20-33-111(64)86(134)65-28-21-34-112(65)87(135)70(51(12)114)108-74(122)53(90)29-35-138-13/h14-16,22-23,44-51,53-65,69-70,113-114H,17-21,24-43,90H2,1-13H3,(H2,91,115)(H,95,119)(H,96,116)(H,97,124)(H,98,129)(H,99,121)(H,100,120)(H,101,128)(H,102,127)(H,103,131)(H,104,130)(H,105,125)(H,106,126)(H,107,123)(H,108,122)(H,117,118)(H,136,137)(H4,92,93,94)/t48-,49-,50-,51+,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,69-,70-/m0/s1

InChIKey=HSKIAUINMKVWAN-BFPMYKABSA-N


Database reference: