BIOPEP-UWM: Report

ID 2822
Name PEP inhibitor
sequence
PPPPGGPQPRPPQG

Function:
Inhibitor of prolyl oligopeptidase (EC 3.4.21.26) (MEROPS ID: S09.001)
 
Number of residues
14
Activity code
am
Activity :
antiamnestic
Chemical mass 1378.5310 Monoisotopic mass 1377.7132
EC50 :
0.00 µM



Bibliographic data:
Authors
Maruyama S., Miyoshi S., Osa T., Tanaka H.
Title
Prolyl endopeptidase inhibitory activity of peptides in the repeated sequence of various proline-rich proteins. J. Ferment. Bioeng.,74(3), 145-148, 1992
Year Source
1992 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES:
[H][C@@](CCC(N)=O)(NC(=O)[C@]1([H])CCCN1C(=O)[C@]1([H])CCCN1C(=O)[C@]([H])(CCCNC(N)=N)NC(=O)[C@]1([H])CCCN1C(=O)[C@]([H])(CCC(N)=O)NC(=O)[C@]1([H])CCCN1C(=O)CNC(=O)CNC(=O)[C@]1([H])CCCN1C(=O)[C@]1([H])CCCN1C(=O)[C@]1([H])CCCN1C(=O)[C@]1([H])CCCN1)C(=O)NCC(O)=O

InChI=1S/C62H95N19O17/c63-46(82)21-19-35(51(88)71-34-50(86)87)72-54(91)42-15-6-28-78(42)59(96)43-16-8-30-80(43)57(94)37(11-2-24-68-62(65)66)73-55(92)41-14-5-26-76(41)58(95)38(20-22-47(64)83)74-53(90)40-13-3-25-75(40)49(85)33-69-48(84)32-70-52(89)39-12-4-27-77(39)60(97)45-18-9-31-81(45)61(98)44-17-7-29-79(44)56(93)36-10-1-23-67-36/h35-45,67H,1-34H2,(H2,63,82)(H2,64,83)(H,69,84)(H,70,89)(H,71,88)(H,72,91)(H,73,92)(H,74,90)(H,86,87)(H4,65,66,68)/t35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-/m0/s1

InChIKey=SVKSXCAQANHUIX-SLUWFFAESA-N



Database reference: