BIOPEP-UWM: Report

ID 2824
Name PEP inhibitor
sequence
MPPPLPTRVDFSLAGALN
Function:
Inhibitor of prolyl oligopeptidase (EC 3.4.21.26) (MEROPS ID: S09.001)
 
Number of residues
18
Activity code
am
Activity :
antiamnestic
Chemical mass 1896.2095 Monoisotopic mass 1894.9943
EC50 :
0.00 µM


Bibliographic data:
Authors
Maruyama S., Ohmori T., Nakagami T.
Title
Prolyl endopeptidase inhibitory activity of a glial fibrillary acidic protein fragment and other proline-rich peptides. Biosci. Biotech. Biochem., 60(2), 358-359, 1996
Year Source
1996 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](C)(O)[C@]([H])(NC(=O)[C@]1([H])CCCN1C(=O)[C@]([H])(CC(C)C)NC(=O)[C@]1([H])CCCN1C(=O)[C@]1([H])CCCN1C(=O)[C@]1([H])CCCN1C(=O)[C@@]([H])(N)CCSC)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)NCC(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(N)=O)C(O)=O

InChI=1S/C86H138N22O24S/c1-43(2)35-53(72(118)94-47(9)69(115)92-41-65(112)93-48(10)70(116)96-54(36-44(3)4)73(119)101-58(85(131)132)39-64(88)111)97-76(122)59(42-109)102-74(120)55(38-50-21-14-13-15-22-50)98-75(121)56(40-66(113)114)99-79(125)67(46(7)8)103-71(117)52(23-16-29-91-86(89)90)95-80(126)68(49(11)110)104-78(124)61-25-17-30-105(61)82(128)57(37-45(5)6)100-77(123)60-24-18-31-106(60)83(129)63-27-20-33-108(63)84(130)62-26-19-32-107(62)81(127)51(87)28-34-133-12/h13-15,21-22,43-49,51-63,67-68,109-110H,16-20,23-42,87H2,1-12H3,(H2,88,111)(H,92,115)(H,93,112)(H,94,118)(H,95,126)(H,96,116)(H,97,122)(H,98,121)(H,99,125)(H,100,123)(H,101,119)(H,102,120)(H,103,117)(H,104,124)(H,113,114)(H,131,132)(H4,89,90,91)/t47-,48-,49+,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,67-,68-/m0/s1

InChIKey=VFRJCRBIPGLNQD-SNCYXXRRSA-N


Database reference: