BIOPEP-UWM: Report

ID 2828
Name PEP inhibitor
sequence
PPAYPPPPVP

Function:
Inhibitor of prolyl oligopeptidase (EC 3.4.21.26) (MEROPS ID: S09.001)
 
Number of residues
10
Activity code
am
Activity :
antiamnestic
Chemical mass 1031.2008 Monoisotopic mass 1030.5470
EC50 :
0.00 µM



Bibliographic data:
Authors
Maruyama S., Ohmori T., Nakagami T.
Title
Prolyl endopeptidase inhibitory activity of a glial fibrillary acidic protein fragment and other proline-rich peptides. Biosci. Biotech. Biochem., 60(2), 358-359, 1996
Year Source
1996 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES:
[H][C@@](C)(NC(=O)[C@]1([H])CCCN1C(=O)[C@]1([H])CCCN1)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(C(C)C)C(=O)N1CCC[C@@]1([H])C(O)=O

InChI=1S/C52H74N10O12/c1-30(2)42(51(72)62-28-10-17-41(62)52(73)74)56-45(66)37-13-6-24-58(37)48(69)39-15-8-26-60(39)50(71)40-16-9-27-61(40)49(70)38-14-7-25-59(38)47(68)35(29-32-18-20-33(63)21-19-32)55-43(64)31(3)54-44(65)36-12-5-23-57(36)46(67)34-11-4-22-53-34/h18-21,30-31,34-42,53,63H,4-17,22-29H2,1-3H3,(H,54,65)(H,55,64)(H,56,66)(H,73,74)/t31-,34-,35-,36-,37-,38-,39-,40-,41-,42-/m0/s1

InChIKey=CKRZFMNPRKIHBC-PZAIXHBZSA-N



Database reference: