BIOPEP-UWM: Report

ID 2832
Name Renin inhibitor
sequence
LW
Function:
Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID A01.007)
 
Number of residues
2
Activity code
ren
Activity :
renin inhibitor
Chemical mass 317.3819 Monoisotopic mass 317.1734
EC50 :
0.00 µM


Bibliographic data:
Authors
Udenigwe C.; Li H.; Aluko R.
Title
Quantitative structure-activity relationship modeling of renin-inhibiting dipeptides. Amino Acids, 42, 1379–1386, 2012
Year Source
2012 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@H](C(=O)N[C@H](C(=O)O)Cc1c[nH]c2c1cccc2)CC(C)C

InChI=1S/C17H23N3O3/c1-10(2)7-13(18)16(21)20-15(17(22)23)8-11-9-19-14-6-4-3-5-12(11)14/h3-6,9-10,13,15,19H,7-8,18H2,1-2H3,(H,20,21)(H,22,23)/t13-,15-/m0/s1

InChIKey: BQVUABVGYYSDCJ-ZFWWWQNUSA-N


Inhibitor of Dipeptidyl-peptidase III (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BIOPEP-UWM database of bioactive peptides (ID 9498); the BRENDA database
Inhibitor of Dipeptidyl-peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8688)
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BindingDB database; the BIOPEP-UWM database of bioactive peptides (ID 3389); the BRENDA database; the EROP-Moscow database
Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 8462)


Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids; the BitterDB database; the ChEMBL database; the PubChem database


Database reference:
AHTPDB: ID 1086; 1172; 1378; 1385; 1445; 1469; 1860; 2043; 2079; 2105; 2150; 2606; 2789; 3298; 3575; 3763; 3855; 3992; 4098; 4141; 4201; 4238; 4389; 4468; 4714; 4952; 5162; 5612; 6161; 6273; 6373

BindingDB: ID 50049754

BioPepDB: ID biopep00934

BIOPEP-UWM database of bioactive peptides: ID 3389; 8462; 8688; 9498

BIOPEP-UWM database of sensory peptides and amino acids: ID 337

BitterDB: ID 828

BRENDA: Ligand Leu-Trp

ChEBI: ID 73590

ChEMBL: ID CHEMBL56154

ChemSpider: ID 5360459

EROP-Moscow: ID E09194

J-GLOBAL: ID 200907041657441765

MBPDB: peptide LW

Metabolights: ID MTBLC73590

Nikkaji: ID J151.283H

PubChem: ID 6992319

SATPdb: ID satpdb27808

SureChEMBL: ID SCHEMBL5369872

ZINC: ID ZINC01570252