BIOPEP-UWM: Report

ID 2837
Name oxitocin
sequence
CYIQNCPLG~
Function:
Neuropeptide
 
Number of residues
9
Activity code
ne
Activity :
neuropeptide
Chemical mass 1009.2027 Monoisotopic mass 1008.4506
EC50 :
0.00 µM


Bibliographic data:
Authors
Hruby V. J., Chow M., Smith D. D.
Title
Conformational and structural considerations in oxitocin-receptor binding and biological activity. Annu. Rev. Pharmacol. Toxicol., 30, 501-534, 1990
Year Source
1990 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES:
[H][C@](N)(CS)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CS)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(N)=O

InChI=1S/C43H68N12O12S2/c1-5-22(4)35(54-40(64)28(50-36(60)25(44)19-68)16-23-8-10-24(56)11-9-23)42(66)49-26(12-13-32(45)57)38(62)51-29(17-33(46)58)39(63)53-30(20-69)43(67)55-14-6-7-31(55)41(65)52-27(15-21(2)3)37(61)48-18-34(47)59/h8-11,21-22,25-31,35,56,68-69H,5-7,12-20,44H2,1-4H3,(H2,45,57)(H2,46,58)(H2,47,59)(H,48,61)(H,49,66)(H,50,60)(H,51,62)(H,52,65)(H,53,63)(H,54,64)/t22-,25-,26-,27-,28-,29-,30-,31-,35-/m0/s1

InChIKey: QAFWZUALRZFGFH-DSZYJQQASA-N


The active form contains disulfide bond between two cysteine residues (1 and 6).


Database reference:
Brainpeps: ID 2

ChemSpider: ID 8460300

EROP-Moscow: ID E00002

HMRbase: ID 10013

J-GLOBAL: ID 200907072973820843

NeuroPep: ID NP05817; NP05849; NP05867; NP05876; NP05886; NP05891; NP05896; NP05901

Nikkaji: ID J353.212G

PepBank: Peptide CYIQNCPLG

PepLife: ID 1713; 1714; 2667

PeptideDB: ID PEP02801; PEP02803; PEP02805; PEP02807; PEP02809; PEP04480; PEP05660; PEP07138; PEP07139; PEP07148;
PEP07149; PEP07150; PEP10049; PEP10050; PEP12195

PubChem: CID 10284830

SATPdb: ID satpdb12919; satpdb23956