BIOPEP-UWM: Report

ID 2862
Name Leu-Valorphin-Arg (Hemorphin-9; LVV-hemorphin 6)
sequence
LVVYPWTQR
Function:
Opioid
 
Number of residues
9
Activity code
op
Activity :
opioid
Chemical mass 1161.3488 Monoisotopic mass 1160.6323
EC50 :
0.00 µM


Bibliographic data:
Authors
Glämsta E. L., Marklund A., Hellmann U., Wernstedt C., Terenius L., Nyberg F.
Title
Isolation and characterization of a hemoglobin-derived opioid peptide from the human pituitary gland. Regulatory Peptides, 34, 169-179, 1991
Year Source
1991 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES:
[H][C@](N)(CC(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CCCNC(N)=N)C(O)=O

InChI=1S/C56H84N14O13/c1-28(2)24-36(57)47(74)67-45(30(5)6)52(79)68-44(29(3)4)51(78)66-41(25-32-16-18-34(72)19-17-32)54(81)70-23-11-15-42(70)50(77)65-40(26-33-27-62-37-13-9-8-12-35(33)37)49(76)69-46(31(7)71)53(80)63-38(20-21-43(58)73)48(75)64-39(55(82)83)14-10-22-61-56(59)60/h8-9,12-13,16-19,27-31,36,38-42,44-46,62,71-72H,10-11,14-15,20-26,57H2,1-7H3,(H2,58,73)(H,63,80)(H,64,75)(H,65,77)(H,66,78)(H,67,74)(H,68,79)(H,69,76)(H,82,83)(H4,59,60,61)/t31-,36+,38+,39+,40+,41+,42+,44+,45+,46+/m1/s1

InChIKey=TYDMAYCCXBUMFX-ZAIVSCQOSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database, the BIOPEP-UWM database of bioactive peptides (ID 3402)
Inhibitor of Dipeptidyl Peptidase III (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BRENDA database


Database reference:
AHTPDB: ID 6380

BioPepDB: ID biopep00922

BIOPEP-UWM database of bioactive peptides: ID 3402

BRENDA: Ligand Leu-Val-Val-Tyr-Pro-Trp-Thr-Gln-Arg

ChemSpider: ID 7988014

EROP-Moscow: ID E01088

J-GLOBAL: ID 200907063254539661

Nikkaji: ID J675.912B

PubChem: CID 9812261

SATPdb: ID satpdb28274