BIOPEP-UWM: Report

ID 2893
Name Neuropeptide
sequence
FMRF~

Function:
Neuropeptide
 
Number of residues
4
Activity code
ne
Activity :
neuropeptide
Chemical mass 598.7594 Monoisotopic mass 598.3041
EC50 :
0.00 µM



Bibliographic data:
Authors
Price D. A., Greenberg M. Y.
Title
Structure of a molluscan cardioexitatory neuropeptide. Science, 197, 670-671, 1977
Year Source
1977 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES:
[H][C@](N)(Cc1ccccc1)C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(Cc1ccccc1)C(N)=O

InChI=1S/C29H42N8O4S/c1-42-16-14-23(35-26(39)21(30)17-19-9-4-2-5-10-19)28(41)36-22(13-8-15-34-29(32)33)27(40)37-24(25(31)38)18-20-11-6-3-7-12-20/h2-7,9-12,21-24H,8,13-18,30H2,1H3,(H2,31,38)(H,35,39)(H,36,41)(H,37,40)(H4,32,33,34)/t21-,22-,23-,24-/m0/s1

InChIKey=WCSPDMCSKYUFBX-ZJZGAYNASA-N

The active form is C-terminal amide.


Inhibitor of Trypanothione-disulfide reductase (EC 1.8.1.12) according to the BRENDA database



Database reference:
BindingDB: ID 50034115

BRENDA: Ligand FMRF-NH2

ChEMBL: ID CHEMBL262202

ChemIDplus: ID 64190-70-1

ChemSpider: ID 8275617

EROP-Moscow: ID E00195

FDA SRS: ID 8953X1KZFL

J-GLOBAL: ID 200907005381272224

NeuroPep: ID NP01144; NP01146; NP01149; NP01156; NP01158; NP01166; NP01189; NP01190; NP01199; NP01201; NP01208; NP01213; NP01220;
NP01235; NP01241; NP01245; NP01248

Nikkaji: ID J353.957A

PeptideDB: ID PEP03754; PEP05880; PEP07186; PEP07187; PEP07188; PEP07189; PEP09984; PEP10097; PEP13824; PEP19536

PubChem: CID 10100083

ZINC: ID ZINC000014953725