BIOPEP-UWM: Report

ID 2951
Name mastoparan from vespa vasalis
sequence
INLKALAALAKKIL~
Function:
Toxic
 
Number of residues
14
Activity code
tox
Activity :
toxic
Chemical mass 1478.9022 Monoisotopic mass 1478.0042
EC50 :
0.00 µM


Bibliographic data:
Authors
Hirai Y., Yasuhara T., Yoshida H., Nakajima T., Fujino M., Kitada C.
Title
A new mast cell degranulating peptide "mastoparan" in the venom of Vespula lewisii. Chem. Pharm. Bull., 27, 1942-1944, 1979
Year Source
1979 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N

InChI=1S/C70H131N19O15/c1-17-40(11)55(75)69(103)88-53(35-54(74)90)68(102)87-52(34-39(9)10)67(101)83-46(25-19-22-28-71)62(96)78-45(16)61(95)86-50(32-37(5)6)65(99)79-42(13)58(92)77-43(14)60(94)85-51(33-38(7)8)66(100)80-44(15)59(93)81-47(26-20-23-29-72)63(97)82-48(27-21-24-30-73)64(98)89-56(41(12)18-2)70(104)84-49(57(76)91)31-36(3)4/h36-53,55-56H,17-35,71-73,75H2,1-16H3,(H2,74,90)(H2,76,91)(H,77,92)(H,78,96)(H,79,99)(H,80,100)(H,81,93)(H,82,97)(H,83,101)(H,84,104)(H,85,94)(H,86,95)(H,87,102)(H,88,103)(H,89,98)/t40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,55-,56-/m0/s1

InChIKey=MASXKPLGZRMBJF-MVSGICTGSA-N


The active form of this peptide is C-terminal amide.


Peptide stimulating GTP hydrolysis according to the ChEMBL database
Antibacterial peptide according to the APD database; the BIOPEP-UWM database of bioactive peptides (ID 5416); the CAMP database; the DBAASP database
Anticancer peptide according to the APD database; the BIOPEP-UWM database of bioactive peptides (ID 2954)
Cell-penetrating peptide according to the CPPsite database
Mast cell degranulating peptide according to the EROP-Moscow database; the PubChem database
Hemolytic peptide according to the the BIOPEP-UWM database of bioactive peptides (ID 2953); the Hemolytik database


Database reference:
ACToR: ID 72093-21-1

APD: ID AP00201

BIOPEP-UWM database of bioactive peptides: ID 2953, 2954, 5416

CAMP: ID CAMPSQ2744

ChEBI: ID 78496

ChEMBL: ID CHEMBL2370408

ChemIdplus: ID 72093-21-1

ChemSpider: ID 4884362

CPPsite: ID 1060; 2640

CTD: ID 72093-21-1

DBAASP: ID 3343

ECHA: ID 686-480-8

EROP-Moscow: ID E00241

Hemolytik: ID 1282; 1732; 2013; 2014; 3753

J-GLOBAL: ID 200907058182681448

Metabolights: ID MTBLC78496

NIAID: ID 72093-21-1

Nikkaji: ID J372.210D

PDB: ID 1D7N

PepBank: Peptide INLKALAALAKKIL

PeptideDB: ID PEP03336

PubChem: CID 6324633

SATPdb: ID satpdb12506

TCDB: ID 1.C.32.1.6