BIOPEP-UWM: Report

ID 2953
Name mastoparan from venom of Vespula levissii
sequence
INLKALAALAKKIL~
Function:
Hemolytic
 
Number of residues
14
Activity code
he
Activity :
haemolytic
Chemical mass 1478.9022 Monoisotopic mass 1478.0042
EC50 :
0.00 µM


Bibliographic data:
Authors
Moerman L., Bosteels S., Noppe W., Willems J., Clynen E., Schoofs L., Thevissen K., Tytgat J., Van Eldere J., Van Der Walt J., Verdonck F.
Title
Antibacterial and antifungal properties of alpha-helical, cationic peptides in the venom of scorpions from southern Africa. Eur. J. Biochem., 269, 4799-4810, 2002
Year Source
2002 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N

InChI=1S/C70H131N19O15/c1-17-40(11)55(75)69(103)88-53(35-54(74)90)68(102)87-52(34-39(9)10)67(101)83-46(25-19-22-28-71)62(96)78-45(16)61(95)86-50(32-37(5)6)65(99)79-42(13)58(92)77-43(14)60(94)85-51(33-38(7)8)66(100)80-44(15)59(93)81-47(26-20-23-29-72)63(97)82-48(27-21-24-30-73)64(98)89-56(41(12)18-2)70(104)84-49(57(76)91)31-36(3)4/h36-53,55-56H,17-35,71-73,75H2,1-16H3,(H2,74,90)(H2,76,91)(H,77,92)(H,78,96)(H,79,99)(H,80,100)(H,81,93)(H,82,97)(H,83,101)(H,84,104)(H,85,94)(H,86,95)(H,87,102)(H,88,103)(H,89,98)/t40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,55-,56-/m0/s1

InChIKey=MASXKPLGZRMBJF-MVSGICTGSA-N


The active form of this peptide is C-terminal amide.


Peptide stimulating GTP hydrolysis according to the ChEMBL database
Antibacterial peptide according to the APD database; the CAMP database; the DBAASP database
Anticancer peptide according to the APD database
Cell-penetrating peptide according to the CPPsite database
Mast cell degranulating peptide according to the EROP-Moscow database; the PubChem database
Toxic peptide according to the the BIOPEP-UWM database of bioactive peptides (ID 2951)


Database reference:
ACToR: ID 72093-21-1

APD: ID AP00201

BIOPEP-UWM database of bioactive peptides: ID 2951

CAMP: ID CAMPSQ2744

ChEBI: ID 78496

ChEMBL: ID CHEMBL2370408

ChemIdplus: ID 72093-21-1

ChemSpider: ID 4884362

CPPsite: ID 1060; 2640

CTD: ID 72093-21-1

DBAASP: ID 3343

ECHA: ID 686-480-8

EROP-Moscow: ID E00241

Hemolytik: ID 1282; 1732; 2013; 2014; 3753

J-GLOBAL: ID 200907058182681448

Metabolights: ID MTBLC78496

NIAID: ID 72093-21-1

Nikkaji: ID J372.210D

PDB: ID 1D7N

PepBank: Peptide INLKALAALAKKIL

PeptideDB: ID PEP03336

PubChem: CID 6324633

SATPdb: ID satpdb12506

TCDB: ID 1.C.32.1.6