BIOPEP-UWM: Report

ID 2960
Name Peptide stimulating insulin release
sequence
GFGSFLGKALKAALKIGANALGGSPQQ
Function:
 
Number of residues
27
Activity code
sti
Activity :
stimulating
Chemical mass 2601.9886 Monoisotopic mass 2600.4394
EC50 :
0.00 µM


Bibliographic data:
Authors
Srinivasan D., Mechkarska M., Abdel-Wahab Y. H., Flatt P. R., Conlon J. M.
Title
Caerulein precursor fragment (CPF) peptides from the skin secretions of Xenopus laevis and Silurana epitropicalis are potent insulin-releasing agents. Biochimie, 95, 429-435, 2013
Year Source
2013 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES:
[H][C@@](C)(NC(=O)CNC(=O)[C@@]([H])(NC(=O)[C@]([H])(CCCCN)NC(=O)[C@]([H])(CC(C)C)NC(=O)[C@]([H])(C)NC(=O)[C@]([H])(C)NC(=O)[C@]([H])(CCCCN)NC(=O)[C@]([H])(CC(C)C)NC(=O)[C@]([H])(C)NC(=O)[C@]([H])(CCCCN)NC(=O)CNC(=O)[C@]([H])(CC(C)C)NC(=O)[C@]([H])(Cc1ccccc1)NC(=O)[C@]([H])(CO)NC(=O)CNC(=O)[C@]([H])(Cc1ccccc1)NC(=O)CN)[C@@H](C)CC)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(=O)NCC(=O)N[C@@]([H])(CO)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CCC(N)=O)C(O)=O

InChI=1S/C118H193N33O33/c1-16-65(10)97(116(181)130-56-93(159)131-66(11)99(164)147-84(52-90(125)156)110(175)135-70(15)101(166)144-78(46-61(2)3)103(168)127-54-92(158)126-55-94(160)139-86(60-153)117(182)151-45-29-37-87(151)115(180)142-76(38-40-88(123)154)108(173)143-77(118(183)184)39-41-89(124)155)150-109(174)75(36-25-28-44-121)141-112(177)81(49-64(8)9)145-100(165)68(13)132-98(163)67(12)133-107(172)74(35-24-27-43-120)140-111(176)80(48-63(6)7)146-102(167)69(14)134-106(171)73(34-23-26-42-119)136-95(161)57-128-104(169)79(47-62(4)5)148-113(178)83(51-72-32-21-18-22-33-72)149-114(179)85(59-152)138-96(162)58-129-105(170)82(137-91(157)53-122)50-71-30-19-17-20-31-71/h17-22,30-33,61-70,73-87,97,152-153H,16,23-29,34-60,119-122H2,1-15H3,(H2,123,154)(H2,124,155)(H2,125,156)(H,126,158)(H,127,168)(H,128,169)(H,129,170)(H,130,181)(H,131,159)(H,132,163)(H,133,172)(H,134,171)(H,135,175)(H,136,161)(H,137,157)(H,138,162)(H,139,160)(H,140,176)(H,141,177)(H,142,180)(H,143,173)(H,144,166)(H,145,165)(H,146,167)(H,147,164)(H,148,178)(H,149,179)(H,150,174)(H,183,184)/t65-,66-,67-,68-,69-,70-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,97-/m0/s1

InChIKey=NGJQBWOJEUPEKT-ZPICWOCPSA-N


Database reference:
EROP-Moscow: ID E12789