BIOPEP-UWM: Report

ID 2962
Name Antibacterial peptide
sequence
GIGKFLHSAGKFGKAFVGEIMKS
Function:
Antibacterial
 
Number of residues
23
Activity code
ab
Activity :
antibacterial
Chemical mass 2409.8403 Monoisotopic mass 2408.2998
EC50 :
0.00 µM


Bibliographic data:
Authors
Zasloff M.
Title
Magainins, a class of antimicrobial peptides from Xenopus Skin: Isolation, characterization of two active forms, and partial cDNA sequence of a precursor. Proc. Natl Acad. Sci. USA, 84, 5449-5453, 1987
Year Source
1987 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: [H][C@@](C)(NC(=O)[C@]([H])(CO)NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@]([H])(CC(C)C)NC(=O)[C@]([H])(CC1=CC=CC=C1)NC(=O)[C@]([H])(CCCCN)NC(=O)CNC(=O)[C@@]([H])(NC(=O)CN)[C@@]([H])(C)CC)C(=O)NCC(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC1=CC=CC=C1)C(=O)NCC(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC1=CC=CC=C1)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CO)C(O)=O)[C@@]([H])(C)CC

InChI=1S/C112H177N29O28S/c1-12-65(7)93(139-86(144)54-117)110(166)122-59-89(147)128-75(39-25-29-46-115)100(156)135-81(51-70-33-19-15-20-34-70)105(161)133-79(49-63(3)4)104(160)136-83(53-72-55-118-62-123-72)106(162)137-84(60-142)108(164)124-67(9)95(151)119-56-87(145)127-74(38-24-28-45-114)99(155)134-80(50-69-31-17-14-18-32-69)97(153)120-57-88(146)126-73(37-23-27-44-113)98(154)125-68(10)96(152)132-82(52-71-35-21-16-22-36-71)107(163)140-92(64(5)6)109(165)121-58-90(148)129-77(41-42-91(149)150)103(159)141-94(66(8)13-2)111(167)131-78(43-48-170-11)102(158)130-76(40-26-30-47-116)101(157)138-85(61-143)112(168)169/h14-22,31-36,55,62-68,73-85,92-94,142-143H,12-13,23-30,37-54,56-61,113-117H2,1-11H3,(H,118,123)(H,119,151)(H,120,153)(H,121,165)(H,122,166)(H,124,164)(H,125,154)(H,126,146)(H,127,145)(H,128,147)(H,129,148)(H,130,158)(H,131,167)(H,132,152)(H,133,161)(H,134,155)(H,135,156)(H,136,160)(H,137,162)(H,138,157)(H,139,144)(H,140,163)(H,141,159)(H,149,150)(H,168,169)/t65-,66-,67-,68-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,92-,93-,94-/m0/s1

InChIKey=OFIZOVDANLLTQD-ZVNXOKPXSA-N


Antiviral peptide according to the APD database; the AVPdb database
Hemolytic peptide according to the DBAASP database


Database reference:
ACToR: ID 108433-99-4

APD: ID AP00771

AVPdb: ID AVP0424

CAMP: ID CAMPSQ109

ChemIDplus: ID 108433-99-4

CTD: ID 108433-99-4

DBAASP: ID 1781

EROP-Moscow: ID E00709

Hemolytik: ID 2442

PeptideDB: ID PEP04290

PubChem: CID 44350363

SATPdb: ID satpdb12738