BIOPEP-UWM: Report

ID 2965
Name Antibacterial peptide
sequence
GFVDFLKKVAGTIANVVT~
Function:
Antibacterial
 
Number of residues
18
Activity code
ab
Activity :
antibacterial
Chemical mass 1878.2128 Monoisotopic mass 1877.0741
EC50 :
0.00 µM


Bibliographic data:
Authors
Rozek T., Waugh R. J., Steinborner S. T., Bowie J. H., Tyler M. J., Wallace J. C.
Title
The Maculatin peptides from the skin glands of the tree frog Litoria genimaculata: a comparison of the structures and antibacterial activities of Maculatin 1.1 and Caerin 1.1. J. Pept. Sci. 4, 111-115, 1998
Year Source
1998 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)NCC(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N

InChI=1S/C88H144N22O23/c1-17-48(12)70(87(132)96-50(14)75(120)100-60(39-62(92)113)82(127)107-68(46(8)9)85(130)108-69(47(10)11)86(131)110-71(51(15)111)73(93)118)109-88(133)72(52(16)112)104-64(115)42-94-74(119)49(13)95-83(128)66(44(4)5)105-77(122)56(33-25-27-35-90)98-76(121)55(32-24-26-34-89)99-78(123)57(36-43(2)3)101-79(124)59(38-54-30-22-19-23-31-54)102-80(125)61(40-65(116)117)103-84(129)67(45(6)7)106-81(126)58(97-63(114)41-91)37-53-28-20-18-21-29-53/h18-23,28-31,43-52,55-61,66-72,111-112H,17,24-27,32-42,89-91H2,1-16H3,(H2,92,113)(H2,93,118)(H,94,119)(H,95,128)(H,96,132)(H,97,114)(H,98,121)(H,99,123)(H,100,120)(H,101,124)(H,102,125)(H,103,129)(H,104,115)(H,105,122)(H,106,126)(H,107,127)(H,108,130)(H,109,133)(H,110,131)(H,116,117)/t48-,49-,50-,51+,52+,55-,56-,57-,58-,59-,60-,61-,66-,67-,68-,69-,70-,71-,72-/m0/s1

InChIKey=METXCEDVVZFIAB-LSRMASGPSA-N


The active form is C-terminal amide.


Database reference:
APD: ID AP00262

CAMP: ID CAMPSQ722; CAMPSQ2819

DBAASP: ID 3896

EROP-Moscow: ID E02864

PeptideDB: ID PEP07691

SATPdb: ID satpdb27732

UniProtKB: Access. No P82068