BIOPEP-UWM: Report

ID 3036
Name insulin secretion inhibitor
sequence
YNVEHAVDYVERA
Function:
Insulin secretion inhibitor
 
Number of residues
13
Activity code
inh
Activity :
inhibitor
Chemical mass 1564.6497 Monoisotopic mass 1563.7294
EC50 :
0.00 µM


Bibliographic data:
Authors
Martin F., Salinas E., Barahona F., Vazquez J., Soria B., Reig J. A.
Title
Engineered peptides corresponding to segments of the H3 domain of syntaxin inhibit insulin release both in intact and permeabilized mouse pancreatic beta cells. Biochem. Biophys. Res. Commun., 248 (1), 83-86, 1998
Year Source
1998 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CC1=CN=CN1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(C)C(O)=O

InChI=1S/C69H101N19O23/c1-31(2)53(86-56(98)34(7)77-61(103)46(26-38-29-74-30-76-38)84-60(102)44(20-22-51(94)95)81-66(108)55(33(5)6)88-64(106)47(27-49(71)91)82-57(99)41(70)24-36-11-15-39(89)16-12-36)67(109)85-48(28-52(96)97)62(104)83-45(25-37-13-17-40(90)18-14-37)63(105)87-54(32(3)4)65(107)80-43(19-21-50(92)93)59(101)79-42(10-9-23-75-69(72)73)58(100)78-35(8)68(110)111/h11-18,29-35,41-48,53-55,89-90H,9-10,19-28,70H2,1-8H3,(H2,71,91)(H,74,76)(H,77,103)(H,78,100)(H,79,101)(H,80,107)(H,81,108)(H,82,99)(H,83,104)(H,84,102)(H,85,109)(H,86,98)(H,87,105)(H,88,106)(H,92,93)(H,94,95)(H,96,97)(H,110,111)(H4,72,73,75)/t34-,35-,41-,42-,43-,44-,45-,46-,47-,48-,53-,54-,55-/m0/s1

InChIKey=BNBAGLXNPVFJMC-HMZPNKQPSA-N


Database reference: