BIOPEP-UWM: Report

ID 3038
Name insulin secretion inhibitor
sequence
IEYNVEHAVDYVE
Function:
insulin secretion inhibitor
 
Number of residues
13
Activity code
inh
Activity :
inhibitor
Chemical mass 1579.6577 Monoisotopic mass 1578.7177
EC50 :
0.00 µM


Bibliographic data:
Authors
Martin F., Salinas E., Barahona F., Vazquez J., Soria B., Reig J. A.
Title
Engineered peptides corresponding to segments of the H3 domain of syntaxin inhibit insulin release both in intact and permeabilized mouse pancreatic beta cells. Biochem. Biophys. Res. Commun., 248 (1), 83-86, 1998
Year Source
1998 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@@](C)(NC(=O)[C@]([H])(CC1=CN=CN1)NC(=O)[C@]([H])(CCC(O)=O)NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CC(N)=O)NC(=O)[C@]([H])(Cc1ccc(O)cc1)NC(=O)[C@]([H])(CCC(O)=O)NC(=O)[C@@]([H])(N)[C@@H](C)CC)C(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCC(O)=O)C(O)=O

InChI=1S/C71H102N16O25/c1-10-35(8)55(73)67(107)77-42(19-22-51(91)92)60(100)80-45(25-37-11-15-40(88)16-12-37)63(103)83-48(28-50(72)90)66(106)87-57(33(4)5)68(108)78-43(20-23-52(93)94)61(101)82-47(27-39-30-74-31-75-39)62(102)76-36(9)59(99)85-56(32(2)3)70(110)84-49(29-54(97)98)64(104)81-46(26-38-13-17-41(89)18-14-38)65(105)86-58(34(6)7)69(109)79-44(71(111)112)21-24-53(95)96/h11-18,30-36,42-49,55-58,88-89H,10,19-29,73H2,1-9H3,(H2,72,90)(H,74,75)(H,76,102)(H,77,107)(H,78,108)(H,79,109)(H,80,100)(H,81,104)(H,82,101)(H,83,103)(H,84,110)(H,85,99)(H,86,105)(H,87,106)(H,91,92)(H,93,94)(H,95,96)(H,97,98)(H,111,112)/t35-,36-,42-,43-,44-,45-,46-,47-,48-,49-,55-,56-,57-,58-/m0/s1

InChIKey=UWVWKQABOXWMBQ-WLLQXDSQSA-N


Database reference: