BIOPEP-UWM: Report

ID 3050
Name CaMKII inhibitor
sequence
YCQRTLREIQILLRF
Function:
Inhibitor of Ca2+/calmodulin-dependent protein kinase (EC 2.7.11.17)
 
Number of residues
15
Activity code
cmk2
Activity :
CaMKII Inhibitor
Chemical mass 1952.3221 Monoisotopic mass 1951.0793
EC50 :
0.00 µM


Bibliographic data:
Authors
Ishida A., Shigeri Y., Tatsu Y., Uegaki K., Kameshita I., Okuno S., Kitani T., Yuamoto N., Fujisawa H.
Title
Critical amino acids residues of AIP, a highly specific inhibitory peptide of calmodulin-dependent protein kinase II. FEBS Lett., 427, 115-118, 1998
Year Source
1998 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(Cc1ccccc1)C(O)=O

InChI=1S/C88H146N26O22S/c1-12-47(9)68(82(132)106-58(30-33-66(91)118)76(126)113-69(48(10)13-2)83(133)108-62(40-46(7)8)80(130)107-60(38-44(3)4)78(128)103-55(23-18-36-99-87(94)95)73(123)110-63(85(135)136)42-50-20-15-14-16-21-50)112-77(127)59(31-34-67(119)120)104-72(122)54(22-17-35-98-86(92)93)102-79(129)61(39-45(5)6)109-84(134)70(49(11)115)114-75(125)56(24-19-37-100-88(96)97)101-74(124)57(29-32-65(90)117)105-81(131)64(43-137)111-71(121)53(89)41-51-25-27-52(116)28-26-51/h14-16,20-21,25-28,44-49,53-64,68-70,115-116,137H,12-13,17-19,22-24,29-43,89H2,1-11H3,(H2,90,117)(H2,91,118)(H,101,124)(H,102,129)(H,103,128)(H,104,122)(H,105,131)(H,106,132)(H,107,130)(H,108,133)(H,109,134)(H,110,123)(H,111,121)(H,112,127)(H,113,126)(H,114,125)(H,119,120)(H,135,136)(H4,92,93,98)(H4,94,95,99)(H4,96,97,100)/t47-,48-,49+,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,68-,69-,70-/m0/s1

InChIKey=OSXAQOCCWDQJMJ-OGTMDSEYSA-N


Database reference: