BIOPEP-UWM: Report

ID 3068
Name human endothelin II
sequence
CSCSSWLDKECVYFCHLDIIW
Function:
vasoconstrictor
 
Number of residues
21
Activity code
vsc
Activity :
vasoconstrictor
Chemical mass 2550.9455 Monoisotopic mass 2549.0850
EC50 :
0.00 µM


Bibliographic data:
Authors
Inoue A., Yanagisawa M., Kimura S., Kasuya Y., Miyauchi T., Goto K., Masaki T.
Title
The human endothelin family: Three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc. Natl Acad. Sci. USA, 86, 2863-2867, 1989
Year Source
1989 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [C@H](N)(CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=C[N]C2=C1C=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC3=CC=C(C=C3)O)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC5=CN=C[N]5)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC6=C[N]C7=C6C=CC=C7)C(O)=O

InChI=1S/C115H164N26O32S4/c1-11-59(9)93(113(170)132-82(115(172)173)41-64-46-120-71-27-19-17-25-68(64)71)141-114(171)94(60(10)12-2)140-105(162)81(44-91(150)151)130-99(156)75(37-57(5)6)125-103(160)79(42-65-47-118-55-121-65)128-109(166)86(52-175)137-101(158)76(38-61-22-14-13-15-23-61)126-100(157)77(39-62-29-31-66(145)32-30-62)131-112(169)92(58(7)8)139-111(168)88(54-177)136-97(154)73(33-34-89(146)147)123-96(153)72(28-20-21-35-116)122-104(161)80(43-90(148)149)129-98(155)74(36-56(3)4)124-102(159)78(40-63-45-119-70-26-18-16-24-67(63)70)127-106(163)84(49-143)134-107(164)85(50-144)135-110(167)87(53-176)138-108(165)83(48-142)133-95(152)69(117)51-174/h13-19,22-27,29-32,45-47,55-60,69,72-88,92-94,119-120,142-145,174-177H,11-12,20-21,28,33-44,48-54,116-117H2,1-10H3,(H,118,121)(H,122,161)(H,123,153)(H,124,159)(H,125,160)(H,126,157)(H,127,163)(H,128,166)(H,129,155)(H,130,156)(H,131,169)(H,132,170)(H,133,152)(H,134,164)(H,135,167)(H,136,154)(H,137,158)(H,138,165)(H,139,168)(H,140,162)(H,141,171)(H,146,147)(H,148,149)(H,150,151)(H,172,173)/t59-,60-,69-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,92-,93-,94-/m0/s1

InChIKey=XBZLMXIYDPWXEV-IYRKOGFYSA-N


Database reference:
ChemSpider: ID 17314130

J-GLOBAL: ID 200907069483438737

NeuroPep: ID NP01117; NP01119; NP01122; NP01124; NP01127; NP01132; NP01134

Nikkaji: ID J353.319K

PeptideDB: ID PEP04380; PEP04994; PEP12945; PEP13116; PEP15091; PEP15967; PEP15970; PEP16595

PubChem: CID 16157828

SATPdb: ID satpdb15812