BIOPEP-UWM: Report

ID 3069
Name human endothelin I
sequence
CSCSSLMDKECVYFCHLDIIW
Function:
vasoconstrictor
 
Number of residues
21
Activity code
vsc
Activity :
vasoconstrictor
Chemical mass 2495.9328 Monoisotopic mass 2494.0462
EC50 :
0.00 µM


Bibliographic data:
Authors
Inoue A., Yanagisawa M., Kimura S., Kasuya Y., Miyauchi T., Goto K., Masaki T.
Title
The human endothelin family: Three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc. Natl Acad. Sci. USA, 86, 2863-2867, 1989
Year Source
1989 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [C@H](N)(CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC3=CN=C[N]3)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC4=C[N]C5=C4C=CC=C5)C(O)=O

InChI=1S/C109H163N25O32S5/c1-12-56(9)87(107(163)125-76(109(165)166)39-60-43-113-65-24-18-17-23-63(60)65)134-108(164)88(57(10)13-2)133-99(155)75(42-85(143)144)123-94(150)70(36-54(5)6)118-97(153)73(40-61-44-112-52-114-61)121-103(159)80(49-168)130-96(152)71(37-58-21-15-14-16-22-58)120-95(151)72(38-59-26-28-62(138)29-27-59)124-106(162)86(55(7)8)132-105(161)82(51-170)129-91(147)67(30-31-83(139)140)116-90(146)66(25-19-20-33-110)115-98(154)74(41-84(141)142)122-92(148)68(32-34-171-11)117-93(149)69(35-53(3)4)119-100(156)78(46-136)127-101(157)79(47-137)128-104(160)81(50-169)131-102(158)77(45-135)126-89(145)64(111)48-167/h14-18,21-24,26-29,43-44,52-57,64,66-82,86-88,113,135-138,167-170H,12-13,19-20,25,30-42,45-51,110-111H2,1-11H3,(H,112,114)(H,115,154)(H,116,146)(H,117,149)(H,118,153)(H,119,156)(H,120,151)(H,121,159)(H,122,148)(H,123,150)(H,124,162)(H,125,163)(H,126,145)(H,127,157)(H,128,160)(H,129,147)(H,130,152)(H,131,158)(H,132,161)(H,133,155)(H,134,164)(H,139,140)(H,141,142)(H,143,144)(H,165,166)/t56-,57-,64-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,86-,87-,88-/m0/s1

InChIKey=IWBLZZSEUHZWPR-ZTNLKOGPSA-N


Database reference:
Brainpeps: ID 88

ChemSpider: ID 17294171

EROP-Moscow: ID E00728

J-GLOBAL: ID 200907031255520183

NeuroPep: ID NP01114; NP01116; NP01118; NP01121; NP01125; NP01126; NP01129; NP01133; NP01136; NP01137

Nikkaji: ID J246.189G

PeptideDB: ID PEP03572; PEP03573; PEP03856; PEP03857; PEP04466; PEP04746; PEP05071; PEP05072; PEP05436; PEP08636; PEP11411; PEP12944; PEP13077; PEP17991

PubChem: CID 16137662

SATPdb: ID satpdb19171; satpdb19238; satpdb24795