BIOPEP-UWM: Report

ID 3108
Name adrenocorticotropin hormone fr.:4-11
sequence
MEHFRWGK

Function:
ACTH is produced due to stress, in the form of physical, emotional, or dietary, signals the brain. ACTH turns signals the adrenal glands to produce cortisol that regulates glucose levels in the blood and activates immune response to foreign invaders such as viruses and bacteria.
 
Number of residues
8
Activity code
re
Activity :
regulating
Chemical mass 1090.2559 Monoisotopic mass 1089.5163
EC50 :
0.00 µM



Bibliographic data:
Authors
Gao X. F., Wong T. C.
Title
NMR studies of adrenocorticotropin hormone peptides in sodium dodecylsulfate and dodecylphosphocholine micelles: proline isomerism and interactions of the peptides with micelles. Biopolymers, 58, 20-32, 2001
Year Source
2001 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [C@H](N)(CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CN=C[N]1)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC3=C[N]C4=C3C=CC=C4)C(=O)NCC(=O)N[C@@H](CCCCN)C(O)=O

InChI=1S/C50H71N15O11S/c1-77-21-18-33(52)43(69)61-36(16-17-42(67)68)46(72)65-40(24-31-26-55-28-59-31)48(74)63-38(22-29-10-3-2-4-11-29)47(73)62-35(15-9-20-56-50(53)54)45(71)64-39(23-30-25-57-34-13-6-5-12-32(30)34)44(70)58-27-41(66)60-37(49(75)76)14-7-8-19-51/h2-6,10-13,25-26,28,33,35-40,57H,7-9,14-24,27,51-52H2,1H3,(H,55,59)(H,58,70)(H,60,66)(H,61,69)(H,62,73)(H,63,74)(H,64,71)(H,65,72)(H,67,68)(H,75,76)(H4,53,54,56)/t33-,35-,36-,37-,38-,39-,40-/m0/s1

InChIKey=ZKBNJKUZBFBIKV-YJXWTMGESA-N




Database reference:
ChemSpider: ID 77431537

PubChem: CID 10418687