BIOPEP-UWM: Report

ID 3109
Name adrenocorticotropin hormone fr.: 4-10
sequence
MEHFRWG

Function:
ACTH is produced due to stress, in the form of physical, emotional, or dietary, signals the brain. ACTH turns signals the adrenal glands to produce cortisol that regulates glucose levels in the blood and activates immune response to foreign invaders such as viruses and bacteria.
 
Number of residues
7
Activity code
re
Activity :
regulating
Chemical mass 962.0841 Monoisotopic mass 961.4216
EC50 :
0.00 µM



Bibliographic data:
Authors
Gao X. F., Wong T. C.
Title
NMR studies of adrenocorticotropin hormone peptides in sodium dodecylsulfate and dodecylphosphocholine micelles: proline isomerism and interactions of the peptides with micelles. Biopolymers, 58, 20-32, 2001
Year Source
2001 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [C@H](N)(CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CN=C[N]1)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC3=C[N]C4=C3C=CC=C4)C(=O)NCC(O)=O

InChI=1S/C44H59N13O10S/c1-68-17-15-29(45)38(62)53-32(13-14-36(58)59)41(65)57-35(20-27-22-48-24-52-27)43(67)55-33(18-25-8-3-2-4-9-25)42(66)54-31(12-7-16-49-44(46)47)40(64)56-34(39(63)51-23-37(60)61)19-26-21-50-30-11-6-5-10-28(26)30/h2-6,8-11,21-22,24,29,31-35,50H,7,12-20,23,45H2,1H3,(H,48,52)(H,51,63)(H,53,62)(H,54,66)(H,55,67)(H,56,64)(H,57,65)(H,58,59)(H,60,61)(H4,46,47,49)/t29-,31-,32-,33-,34-,35-/m0/s1

InChIKey=HAAUASBAIUJHAN-LXOXETEGSA-N



Database reference:
ChemSpider: ID 110338

PubChem: CID 123787