BIOPEP-UWM: Report

ID 3137
Name Esculentin-1b fragment: 1-18
sequence
GIFSKLAGKKLKNLLISG
Function:
Antibcaterial
 
Number of residues
18
Activity code
ab
Activity :
antibacterial
Chemical mass 1887.3070 Monoisotopic mass 1886.1681
EC50 :
0.00 µM


Bibliographic data:
Authors
Marcellini L., Borro M., Gentile G., Rinaldi A. C., Stella L., Aimola P., Barra D., Mangoni M. L.
Title
Esculentin-1b(1-18)-a membrane-active antimicrobial peptide that synergizes with antibiotics and modifies the expression level of a limited number of proteins in Escherichia coli. FEBS J., 276, 5647-5664, 2009
Year Source
2009 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: NCC(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)NCC(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CO)C(=O)NCC(=O)O

InChI=1S/C47H75N15O15S/c1-23(2)16-31(45(74)61-14-6-10-34(61)44(73)58-30(18-35(50)63)42(71)56-28(47(76)77)8-4-5-13-48)60-40(69)27(11-12-37(65)66)55-41(70)29(17-25-20-52-22-53-25)57-43(72)33-9-7-15-62(33)46(75)32(19-36(51)64)59-38(67)24(3)54-39(68)26(49)21-78/h20,22-24,26-34,78H,4-19,21,48-49H2,1-3H3,(H2,50,63)(H2,51,64)(H,52,53)(H,54,68)(H,55,70)(H,56,71)(H,57,72)(H,58,73)(H,59,67)(H,60,69)(H,65,66)(H,76,77)/t24-,26-,27-,28-,29-,30-,31-,32-,33-,34-/m0/s1

InChIKey=ZPAYXAMKTJHDPB-WHBJAZBXSA-N


Database reference:
PepBank: Peptide GIFSKLAGKKLKNLLISG