BIOPEP-UWM: Report

ID 3139
Name erythropoietin receptor agonist peptide
sequence
EAQGCRWGWVGNCKEWLGDEYAKNTGTPAEKGKSRNPP
Function:
Erythropoietin receptor agonist
 
Number of residues
38
Activity code
sti
Activity :
stimulating
Chemical mass 4221.5971 Monoisotopic mass 4218.9690
EC50 :
0.00 µM


Bibliographic data:
Authors
McConnell S. J., Dinh T., Le M-H., Brown S. J., Becherer K. et al.
Title
Isolation of erythropoietin receptor agonist peptides using evolved phage libraries. Biol. Chem., 379, 1279-1286 (1998)
Year Source
1998 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(CCC(O)=O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)NCC(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)NCC(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)NCC(=O)N[C@@]([H])([C@@H](C)O)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CCCCN)C(=O)NCC(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(O)=O

InChI=1S/C183H275N55O57S2/c1-88(2)67-117(225-167(280)121(71-98-78-201-106-34-15-12-31-102(98)106)228-165(278)115(51-56-144(257)258)223-159(272)110(38-19-23-61-187)221-174(287)128(87-297)232-168(281)122(72-133(190)244)213-139(250)83-206-176(289)147(89(3)4)234-170(283)120(70-97-77-200-105-33-14-11-30-101(97)105)212-137(248)80-205-157(270)119(69-96-76-199-104-32-13-10-29-100(96)104)227-161(274)111(39-24-62-197-182(193)194)222-173(286)127(86-296)215-140(251)82-203-155(268)113(49-53-132(189)243)217-150(263)90(5)208-153(266)103(188)48-54-142(253)254)156(269)204-81-138(249)214-124(75-146(261)262)169(282)224-116(52-57-145(259)260)164(277)226-118(68-95-44-46-99(242)47-45-95)166(279)209-91(6)151(264)216-109(37-18-22-60-186)160(273)229-123(73-134(191)245)171(284)235-148(93(8)240)177(290)207-84-141(252)233-149(94(9)241)180(293)236-64-26-41-129(236)175(288)210-92(7)152(265)218-114(50-55-143(255)256)163(276)219-107(35-16-20-58-184)154(267)202-79-136(247)211-108(36-17-21-59-185)158(271)231-126(85-239)172(285)220-112(40-25-63-198-183(195)196)162(275)230-125(74-135(192)246)178(291)237-65-27-42-130(237)179(292)238-66-28-43-131(238)181(294)295/h10-15,29-34,44-47,76-78,88-94,103,107-131,147-149,199-201,239-242,296-297H,16-28,35-43,48-75,79-87,184-188H2,1-9H3,(H2,189,243)(H2,190,244)(H2,191,245)(H2,192,246)(H,202,267)(H,203,268)(H,204,269)(H,205,270)(H,206,289)(H,207,290)(H,208,266)(H,209,279)(H,210,288)(H,211,247)(H,212,248)(H,213,250)(H,214,249)(H,215,251)(H,216,264)(H,217,263)(H,218,265)(H,219,276)(H,220,285)(H,221,287)(H,222,286)(H,223,272)(H,224,282)(H,225,280)(H,226,277)(H,227,274)(H,228,278)(H,229,273)(H,230,275)(H,231,271)(H,232,281)(H,233,252)(H,234,283)(H,235,284)(H,253,254)(H,255,256)(H,257,258)(H,259,260)(H,261,262)(H,294,295)(H4,193,194,197)(H4,195,196,198)/t90-,91-,92-,93+,94+,103-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,147-,148-,149-/m0/s1

InChIKey=GFMRFYRFQXHARQ-FARFOZSGSA-N


Database reference: