BIOPEP-UWM: Report

ID 3140
Name erythropoietin receptor agonist peptide
sequence
DVEVCRGGWVGHCNAWLRDEYNRQPKKPVQQQVVYSTR
Function:
Erythropoietin receptor agonist
 
Number of residues
38
Activity code
sti
Activity :
stimulating
Chemical mass 4502.9964 Monoisotopic mass 4500.2013
EC50 :
0.00 µM


Bibliographic data:
Authors
McConnell S. J., Dinh T., Le M-H., Brown S. J., Becherer K. et al.
Title
Isolation of erythropoietin receptor agonist peptides using evolved phage libraries. Biol. Chem., 379, 1279-1286 (1998)
Year Source
1998 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(CC(O)=O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)NCC(=O)NCC(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CC1=CN=CN1)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])(CCCNC(N)=N)C(O)=O

InChI=1S/C196H302N62O57S2/c1-91(2)71-124(241-173(295)128(75-103-82-220-111-34-20-18-32-108(103)111)240-158(280)98(15)225-169(291)130(78-142(204)267)244-180(302)134(88-316)248-174(296)129(76-104-83-214-90-224-104)227-146(271)86-223-183(305)151(92(3)4)251-177(299)127(74-102-81-219-110-33-19-17-31-107(102)110)226-145(270)85-221-144(269)84-222-160(282)112(37-25-65-215-193(206)207)228-179(301)135(89-317)249-187(309)153(94(7)8)252-168(290)120(56-62-148(274)275)236-184(306)152(93(5)6)250-159(281)109(199)77-149(276)277)170(292)229-115(39-27-67-217-195(210)211)163(285)245-132(80-150(278)279)176(298)233-119(55-61-147(272)273)166(288)242-125(72-100-43-47-105(261)48-44-100)171(293)243-131(79-143(205)268)175(297)230-114(38-26-66-216-194(208)209)162(284)238-122(54-60-141(203)266)191(313)257-69-29-41-136(257)181(303)234-113(35-21-23-63-197)161(283)237-121(36-22-24-64-198)190(312)258-70-30-42-137(258)182(304)254-154(95(9)10)185(307)235-117(52-58-139(201)264)165(287)231-116(51-57-138(200)263)164(286)232-118(53-59-140(202)265)167(289)253-156(97(13)14)188(310)255-155(96(11)12)186(308)246-126(73-101-45-49-106(262)50-46-101)172(294)247-133(87-259)178(300)256-157(99(16)260)189(311)239-123(192(314)315)40-28-68-218-196(212)213/h17-20,31-34,43-50,81-83,90-99,109,112-137,151-157,219-220,259-262,316-317H,21-30,35-42,51-80,84-89,197-199H2,1-16H3,(H2,200,263)(H2,201,264)(H2,202,265)(H2,203,266)(H2,204,267)(H2,205,268)(H,214,224)(H,221,269)(H,222,282)(H,223,305)(H,225,291)(H,226,270)(H,227,271)(H,228,301)(H,229,292)(H,230,297)(H,231,287)(H,232,286)(H,233,298)(H,234,303)(H,235,307)(H,236,306)(H,237,283)(H,238,284)(H,239,311)(H,240,280)(H,241,295)(H,242,288)(H,243,293)(H,244,302)(H,245,285)(H,246,308)(H,247,294)(H,248,296)(H,249,309)(H,250,281)(H,251,299)(H,252,290)(H,253,289)(H,254,304)(H,255,310)(H,256,300)(H,272,273)(H,274,275)(H,276,277)(H,278,279)(H,314,315)(H4,206,207,215)(H4,208,209,216)(H4,210,211,217)(H4,212,213,218)/t98-,99+,109-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,151-,152-,153-,154-,155-,156-,157-/m0/s1

InChIKey=NXBKOVWDLPEWJF-OVIJGLEKSA-N


Database reference: