BIOPEP-UWM: Report

ID 3141
Name erythropoietin receptor agonist peptide
sequence
SLEPCRGGWVGHCNEWQRDEYAINPKWPNAPIEDPNPL
Function:
Erythropoietin receptor agonist
 
Number of residues
38
Activity code
sti
Activity :
stimulating
Chemical mass 4389.7881 Monoisotopic mass 4387.0263
EC50 :
0.00 µM


Bibliographic data:
Authors
McConnell S. J., Dinh T., Le M-H., Brown S. J., Becherer K. et al.
Title
Isolation of erythropoietin receptor agonist peptides using evolved phage libraries. Biol. Chem., 379, 1279-1286 (1998)
Year Source
1998 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(CO)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)NCC(=O)NCC(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CC1=CN=CN1)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(C)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CC(N)=O)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CC(C)C)C(O)=O

InChI=1S/C195H283N55O58S2/c1-13-96(9)157(186(300)238-131(79-146(202)257)191(305)248-66-27-40-136(248)178(292)226-114(37-21-22-60-196)163(277)235-129(74-103-84-212-112-36-20-17-33-108(103)112)189(303)247-65-28-41-137(247)179(293)234-126(76-143(199)254)169(283)218-99(12)187(301)245-63-25-45-141(245)183(297)244-158(97(10)14-2)185(299)227-119(53-58-152(265)266)167(281)236-132(81-155(271)272)192(306)250-68-29-42-138(250)180(294)237-130(78-145(201)256)190(304)249-67-30-43-139(249)181(295)239-133(193(307)308)70-94(5)6)243-159(273)98(11)217-168(282)122(71-100-46-48-105(252)49-47-100)230-165(279)117(51-56-150(261)262)225-174(288)128(80-154(269)270)233-162(276)115(39-24-62-209-195(205)206)222-164(278)116(50-55-142(198)253)223-171(285)124(73-102-83-211-111-35-19-16-32-107(102)111)231-166(280)118(52-57-151(263)264)224-173(287)127(77-144(200)255)232-177(291)134(90-309)240-172(286)125(75-104-85-207-92-216-104)220-149(260)88-215-184(298)156(95(7)8)242-175(289)123(72-101-82-210-110-34-18-15-31-106(101)110)219-148(259)87-213-147(258)86-214-161(275)113(38-23-61-208-194(203)204)221-176(290)135(91-310)241-182(296)140-44-26-64-246(140)188(302)120(54-59-153(267)268)228-170(284)121(69-93(3)4)229-160(274)109(197)89-251/h15-20,31-36,46-49,82-85,92-99,109,113-141,156-158,210-212,251-252,309-310H,13-14,21-30,37-45,50-81,86-91,196-197H2,1-12H3,(H2,198,253)(H2,199,254)(H2,200,255)(H2,201,256)(H2,202,257)(H,207,216)(H,213,258)(H,214,275)(H,215,298)(H,217,282)(H,218,283)(H,219,259)(H,220,260)(H,221,290)(H,222,278)(H,223,285)(H,224,287)(H,225,288)(H,226,292)(H,227,299)(H,228,284)(H,229,274)(H,230,279)(H,231,280)(H,232,291)(H,233,276)(H,234,293)(H,235,277)(H,236,281)(H,237,294)(H,238,300)(H,239,295)(H,240,286)(H,241,296)(H,242,289)(H,243,273)(H,244,297)(H,261,262)(H,263,264)(H,265,266)(H,267,268)(H,269,270)(H,271,272)(H,307,308)(H4,203,204,208)(H4,205,206,209)/t96-,97-,98-,99-,109-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,156-,157-,158-/m0/s1

InChIKey=SKLCOZCIAUBVSF-FNSXSHGNSA-N


Database reference: