BIOPEP-UWM: Report

ID 3142
Name erythropoietin receptor agonist peptide
sequence
QVDTCTRGWVGHCNAWMGDEYAKTPGLPPMPQSDYLKPR
Function:
Erythropoietin receptor agonist
 
Number of residues
39
Activity code
sti
Activity :
stimulating
Chemical mass 4406.9481 Monoisotopic mass 4404.0271
EC50 :
0.00 µM


Bibliographic data:
Authors
McConnell S. J., Dinh T., Le M-H., Brown S. J., Becherer K. et al.
Title
Isolation of erythropoietin receptor agonist peptides using evolved phage libraries. Biol. Chem., 379, 1279-1286 (1998)
Year Source
1998 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(CCC(N)=O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)NCC(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CC1=CN=CN1)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(CCSC)C(=O)NCC(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N1CCC[C@@]1([H])C(=O)NCC(=O)N[C@@]([H])(CC(C)C)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCSC)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCCNC(N)=N)C(O)=O

InChI=1S/C193H290N54O57S4/c1-93(2)71-122(167(279)225-119(36-21-23-61-195)186(298)243-64-28-41-138(243)181(293)227-121(191(303)304)38-25-63-206-193(202)203)229-168(280)124(74-103-46-50-108(253)51-47-103)231-172(284)130(80-150(265)266)233-175(287)133(89-248)235-163(275)116(53-56-142(198)255)223-179(291)137-40-27-65-244(137)187(299)120(59-70-308-15)226-180(292)139-42-29-66-245(139)189(301)140-43-30-68-247(140)188(300)132(72-94(3)4)219-147(260)87-211-178(290)136-39-26-67-246(136)190(302)156(101(13)251)242-164(276)115(35-20-22-60-194)220-157(269)97(9)214-165(277)123(73-102-44-48-107(252)49-45-102)230-162(274)117(54-57-148(261)262)221-171(283)129(79-149(263)264)218-145(258)86-210-161(273)118(58-69-307-14)222-169(281)126(76-105-83-208-113-34-19-17-32-110(105)113)228-158(270)98(10)215-166(278)128(78-143(199)256)232-176(288)134(90-305)236-170(282)127(77-106-84-204-92-213-106)217-146(259)88-212-182(294)152(95(5)6)239-173(285)125(75-104-82-207-112-33-18-16-31-109(104)112)216-144(257)85-209-160(272)114(37-24-62-205-192(200)201)224-184(296)154(99(11)249)241-177(289)135(91-306)237-185(297)155(100(12)250)240-174(286)131(81-151(267)268)234-183(295)153(96(7)8)238-159(271)111(196)52-55-141(197)254/h16-19,31-34,44-51,82-84,92-101,111,114-140,152-156,207-208,248-253,305-306H,20-30,35-43,52-81,85-91,194-196H2,1-15H3,(H2,197,254)(H2,198,255)(H2,199,256)(H,204,213)(H,209,272)(H,210,273)(H,211,290)(H,212,294)(H,214,277)(H,215,278)(H,216,257)(H,217,259)(H,218,258)(H,219,260)(H,220,269)(H,221,283)(H,222,281)(H,223,291)(H,224,296)(H,225,279)(H,226,292)(H,227,293)(H,228,270)(H,229,280)(H,230,274)(H,231,284)(H,232,288)(H,233,287)(H,234,295)(H,235,275)(H,236,282)(H,237,297)(H,238,271)(H,239,285)(H,240,286)(H,241,289)(H,242,276)(H,261,262)(H,263,264)(H,265,266)(H,267,268)(H,303,304)(H4,200,201,205)(H4,202,203,206)/t97-,98-,99+,100+,101+,111-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,152-,153-,154-,155-,156-/m0/s1

InChIKey=OZCWBPZTZVLJNL-LZULAZNJSA-N


Database reference: