BIOPEP-UWM: Report

ID 3143
Name erythropoietin receptor agonist peptide
sequence
GLGACRRGWVGHCNDWLNDEYAKKPGYAMPDGYPHNGT
Function:
Erythropoietin receptor agonist
 
Number of residues
38
Activity code
sti
Activity :
stimulating
Chemical mass 4207.5967 Monoisotopic mass 4204.8784
EC50 :
0.00 µM


Bibliographic data:
Authors
McConnell S. J., Dinh T., Le M-H., Brown S. J., Becherer K. et al.
Title
Isolation of erythropoietin receptor agonist peptides using evolved phage libraries. Biol. Chem., 379, 1279-1286 (1998)
Year Source
1998 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@@](C)(NC(=O)CNC(=O)[C@]([H])(CC(C)C)NC(=O)CN)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)NCC(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CC1=CN=CN1)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N1CCC[C@@]1([H])C(=O)NCC(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCSC)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CC(O)=O)C(=O)NCC(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CC1=CN=CN1)C(=O)N[C@@]([H])(CC(N)=O)C(=O)NCC(=O)N[C@@]([H])([C@@H](C)O)C(O)=O

InChI=1S/C184H265N55O54S3/c1-89(2)59-116(212-139(247)74-187)156(266)202-79-140(248)209-92(7)152(262)233-131(85-294)173(283)219-112(32-21-54-198-184(193)194)159(269)218-110(31-20-53-197-183(191)192)155(265)201-80-141(249)214-120(64-99-75-199-108-27-14-12-25-106(99)108)172(282)236-150(91(5)6)178(288)206-83-143(251)215-122(66-101-77-195-87-207-101)166(276)234-132(86-295)174(284)228-126(70-138(190)246)169(279)230-129(73-149(260)261)171(281)225-121(65-100-76-200-109-28-15-13-26-107(100)109)165(275)223-117(60-90(3)4)164(274)227-125(69-137(189)245)168(278)229-128(72-148(258)259)170(280)220-113(48-49-146(254)255)161(271)224-119(62-97-38-44-104(242)45-39-97)163(273)211-93(8)153(263)217-111(29-16-18-51-185)160(270)222-114(30-17-19-52-186)179(289)237-55-22-33-133(237)175(285)205-82-142(250)213-118(61-96-36-42-103(241)43-37-96)162(272)210-94(9)154(264)221-115(50-58-296-11)180(290)238-56-23-34-134(238)177(287)232-127(71-147(256)257)158(268)203-81-144(252)216-130(63-98-40-46-105(243)47-41-98)181(291)239-57-24-35-135(239)176(286)231-123(67-102-78-196-88-208-102)167(277)226-124(68-136(188)244)157(267)204-84-145(253)235-151(95(10)240)182(292)293/h12-15,25-28,36-47,75-78,87-95,110-135,150-151,199-200,240-243,294-295H,16-24,29-35,48-74,79-86,185-187H2,1-11H3,(H2,188,244)(H2,189,245)(H2,190,246)(H,195,207)(H,196,208)(H,201,265)(H,202,266)(H,203,268)(H,204,267)(H,205,285)(H,206,288)(H,209,248)(H,210,272)(H,211,273)(H,212,247)(H,213,250)(H,214,249)(H,215,251)(H,216,252)(H,217,263)(H,218,269)(H,219,283)(H,220,280)(H,221,264)(H,222,270)(H,223,275)(H,224,271)(H,225,281)(H,226,277)(H,227,274)(H,228,284)(H,229,278)(H,230,279)(H,231,286)(H,232,287)(H,233,262)(H,234,276)(H,235,253)(H,236,282)(H,254,255)(H,256,257)(H,258,259)(H,260,261)(H,292,293)(H4,191,192,197)(H4,193,194,198)/t92-,93-,94-,95+,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,150-,151-/m0/s1

InChIKey=HOTCFXBZRVQQNS-DPIJDZNNSA-N


Database reference: