BIOPEP-UWM: Report

ID 3144
Name erythropoietin receptor agonist peptide
sequence
EGEVCLPGWVGHCKYWLMDEYANIPRNPTPRSNELKPP
Function:
Erythropoietin receptor agonist
 
Number of residues
38
Activity code
sti
Activity :
stimulating
Chemical mass 4397.9582 Monoisotopic mass 4395.0960
EC50 :
0.00 µM


Bibliographic data:
Authors
McConnell S. J., Dinh T., Le M-H., Brown S. J., Becherer K. et al.
Title
Isolation of erythropoietin receptor agonist peptides using evolved phage libraries. Biol. Chem., 379, 1279-1286 (1998)
Year Source
1998 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(CCC(O)=O)C(=O)NCC(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1CCC[C@@]1([H])C(=O)NCC(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CC1=CN=CN1)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(O)=O

InChI=1S/C197H295N53O56S3/c1-16-102(12)159(193(303)247-70-29-42-141(247)184(294)225-118(39-25-66-209-196(204)205)164(274)237-136(85-148(203)257)191(301)246-69-28-44-143(246)186(296)244-160(104(14)252)194(304)248-71-30-43-142(248)185(295)226-119(40-26-67-210-197(206)207)165(275)238-137(93-251)180(290)234-132(83-146(201)255)176(286)222-121(57-61-154(265)266)166(276)229-126(76-98(4)5)172(282)227-124(38-22-24-65-199)189(299)249-72-31-45-144(249)192(302)250-73-32-46-145(250)195(305)306)243-179(289)133(84-147(202)256)228-161(271)103(13)217-170(280)127(78-105-47-51-110(253)52-48-105)231-167(277)122(58-62-155(267)268)223-177(287)134(86-156(269)270)235-168(278)123(63-74-309-15)224-171(281)125(75-97(2)3)230-174(284)130(81-108-88-212-116-36-20-18-34-113(108)116)233-173(283)128(79-106-49-53-111(254)54-50-106)232-163(273)117(37-21-23-64-198)221-181(291)138(94-307)239-175(285)131(82-109-89-208-96-216-109)220-151(260)92-215-187(297)157(100(8)9)241-178(288)129(80-107-87-211-115-35-19-17-33-112(107)115)219-150(259)91-214-183(293)140-41-27-68-245(140)190(300)135(77-99(6)7)236-182(292)139(95-308)240-188(298)158(101(10)11)242-169(279)120(56-60-153(263)264)218-149(258)90-213-162(272)114(200)55-59-152(261)262/h17-20,33-36,47-54,87-89,96-104,114,117-145,157-160,211-212,251-254,307-308H,16,21-32,37-46,55-86,90-95,198-200H2,1-15H3,(H2,201,255)(H2,202,256)(H2,203,257)(H,208,216)(H,213,272)(H,214,293)(H,215,297)(H,217,280)(H,218,258)(H,219,259)(H,220,260)(H,221,291)(H,222,286)(H,223,287)(H,224,281)(H,225,294)(H,226,295)(H,227,282)(H,228,271)(H,229,276)(H,230,284)(H,231,277)(H,232,273)(H,233,283)(H,234,290)(H,235,278)(H,236,292)(H,237,274)(H,238,275)(H,239,285)(H,240,298)(H,241,288)(H,242,279)(H,243,289)(H,244,296)(H,261,262)(H,263,264)(H,265,266)(H,267,268)(H,269,270)(H,305,306)(H4,204,205,209)(H4,206,207,210)/t102-,103-,104+,114-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,157-,158-,159-,160-/m0/s1

InChIKey=DLJHBYDPEINNAO-FOUZILTASA-N


Database reference: