BIOPEP-UWM: Report

ID 3145
Name erythropoietin receptor agonist peptide
sequence
DFDVCRRGWVGHCKDWLSDEYASNPSYPVPHSYYLNPP
Function:
Erythropoietin receptor agonist
 
Number of residues
38
Activity code
sti
Activity :
stimulating
Chemical mass 4471.8439 Monoisotopic mass 4468.9994
EC50 :
0.00 µM


Bibliographic data:
Authors
McConnell S. J., Dinh T., Le M-H., Brown S. J., Becherer K. et al.
Title
Isolation of erythropoietin receptor agonist peptides using evolved phage libraries. Biol. Chem., 379, 1279-1286 (1998)
Year Source
1998 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2c1cccc2)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2c1cccc2)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)O

InChI=1S/C203H281N53O59S2/c1-99(2)68-127(173(286)241-142(81-155(207)266)198(311)255-66-26-40-152(255)199(312)256-67-27-41-153(256)201(314)315)230-176(289)131(72-107-44-52-115(262)53-45-107)233-177(290)132(73-108-46-54-116(263)55-47-108)234-185(298)144(92-258)245-180(293)136(78-113-88-213-98-221-113)239-191(304)150-38-25-65-254(150)200(313)165(103(9)10)251-193(306)151-39-24-64-253(151)196(309)140(74-109-48-56-117(264)57-49-109)240-188(301)146(94-260)246-192(305)149-37-23-63-252(149)197(310)141(80-154(206)265)242-187(300)143(91-257)243-166(279)104(11)222-172(285)129(71-106-42-50-114(261)51-43-106)232-171(284)126(58-59-158(269)270)228-181(294)137(82-160(273)274)238-186(299)145(93-259)244-174(287)128(69-100(3)4)231-178(291)134(76-111-86-217-122-33-18-16-31-119(111)122)235-182(295)138(83-161(275)276)236-170(283)124(34-19-20-60-204)226-189(302)147(95-316)247-179(292)135(77-112-87-212-97-220-112)224-157(268)90-219-194(307)163(101(5)6)249-183(296)133(75-110-85-216-121-32-17-15-30-118(110)121)223-156(267)89-218-168(281)123(35-21-61-214-202(208)209)225-169(282)125(36-22-62-215-203(210)211)227-190(303)148(96-317)248-195(308)164(102(7)8)250-184(297)139(84-162(277)278)237-175(288)130(70-105-28-13-12-14-29-105)229-167(280)120(205)79-159(271)272/h12-18,28-33,42-57,85-88,97-104,120,123-153,163-165,216-217,257-264,316-317H,19-27,34-41,58-84,89-96,204-205H2,1-11H3,(H2,206,265)(H2,207,266)(H,212,220)(H,213,221)(H,218,281)(H,219,307)(H,222,285)(H,223,267)(H,224,268)(H,225,282)(H,226,302)(H,227,303)(H,228,294)(H,229,280)(H,230,289)(H,231,291)(H,232,284)(H,233,290)(H,234,298)(H,235,295)(H,236,283)(H,237,288)(H,238,299)(H,239,304)(H,240,301)(H,241,286)(H,242,300)(H,243,279)(H,244,287)(H,245,293)(H,246,305)(H,247,292)(H,248,308)(H,249,296)(H,250,297)(H,251,306)(H,269,270)(H,271,272)(H,273,274)(H,275,276)(H,277,278)(H,314,315)(H4,208,209,214)(H4,210,211,215)/t104-,120-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,163-,164-,165-/m0/s1

InChIKey: FTUWSBRCCGFMTA-RBLRZEBGSA-N


erythropoietin-stimulates red blood cells creation


Database reference: