BIOPEP-UWM: Report

ID 3149
Name erythropoietin receptor agonist peptide
sequence
NIQGCIRGWVGQCKDWLRDEYAREHTNQETPNNLLNPP
Function:
Erythropoietin receptor agonist
 
Number of residues
38
Activity code
sti
Activity :
stimulating
Chemical mass 4466.8752 Monoisotopic mass 4464.1174
EC50 :
0.00 µM


Bibliographic data:
Authors
McConnell S. J., Dinh T., Le M-H., Brown S. J., Becherer K. et al.
Title
Isolation of erythropoietin receptor agonist peptides using evolved phage libraries. Biol. Chem., 379, 1279-1286 (1998)
Year Source
1998 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](C)(O)[C@]([H])(NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@]([H])(CCC(O)=O)NC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)[C@]([H])(C)NC(=O)[C@]([H])(Cc1ccc(O)cc1)NC(=O)[C@]([H])(CCC(O)=O)NC(=O)[C@]([H])(CC(O)=O)NC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)[C@]([H])(CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@]([H])(CC(O)=O)NC(=O)[C@]([H])(CCCCN)NC(=O)[C@]([H])(CS)NC(=O)[C@]([H])(CCC(N)=O)NC(=O)CNC(=O)[C@@]([H])(NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CS)NC(=O)CNC(=O)[C@]([H])(CCC(N)=O)NC(=O)[C@@]([H])(NC(=O)[C@@]([H])(N)CC(N)=O)[C@@]([H])(C)CC)[C@@]([H])(C)CC)C(C)C)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@]([H])(C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(O)=O)[C@@]([H])(C)O

InChI=1S/C192H294N60O60S2/c1-16-91(11)151(246-156(278)103(194)71-137(198)259)183(305)231-110(45-51-134(195)256)158(280)216-82-144(266)222-129(84-313)180(302)247-152(92(12)17-2)184(306)230-106(35-24-58-210-190(203)204)157(279)215-81-143(265)221-120(68-97-78-213-104-32-20-18-30-101(97)104)177(299)245-150(90(9)10)182(304)217-83-142(264)220-111(46-52-135(196)257)162(284)244-130(85-314)179(301)225-107(34-22-23-57-193)160(282)240-127(77-149(275)276)176(298)236-121(69-98-79-214-105-33-21-19-31-102(98)105)171(293)233-116(64-87(3)4)168(290)224-109(37-26-60-212-192(207)208)161(283)239-126(76-148(273)274)175(297)229-114(49-55-146(269)270)164(286)235-119(67-96-41-43-100(255)44-42-96)167(289)219-93(13)155(277)223-108(36-25-59-211-191(205)206)159(281)226-113(48-54-145(267)268)165(287)237-122(70-99-80-209-86-218-99)178(300)248-153(94(14)253)185(307)242-125(74-140(201)262)172(294)228-112(47-53-136(197)258)163(285)227-115(50-56-147(271)272)166(288)249-154(95(15)254)188(310)250-61-27-38-131(250)181(303)241-124(73-139(200)261)174(296)238-123(72-138(199)260)173(295)234-117(65-88(5)6)169(291)232-118(66-89(7)8)170(292)243-128(75-141(202)263)186(308)251-62-28-39-132(251)187(309)252-63-29-40-133(252)189(311)312/h18-21,30-33,41-44,78-80,86-95,103,106-133,150-154,213-214,253-255,313-314H,16-17,22-29,34-40,45-77,81-85,193-194H2,1-15H3,(H2,195,256)(H2,196,257)(H2,197,258)(H2,198,259)(H2,199,260)(H2,200,261)(H2,201,262)(H2,202,263)(H,209,218)(H,215,279)(H,216,280)(H,217,304)(H,219,289)(H,220,264)(H,221,265)(H,222,266)(H,223,277)(H,224,290)(H,225,301)(H,226,281)(H,227,285)(H,228,294)(H,229,297)(H,230,306)(H,231,305)(H,232,291)(H,233,293)(H,234,295)(H,235,286)(H,236,298)(H,237,287)(H,238,296)(H,239,283)(H,240,282)(H,241,303)(H,242,307)(H,243,292)(H,244,284)(H,245,299)(H,246,278)(H,247,302)(H,248,300)(H,249,288)(H,267,268)(H,269,270)(H,271,272)(H,273,274)(H,275,276)(H,311,312)(H4,203,204,210)(H4,205,206,211)(H4,207,208,212)/t91-,92-,93-,94+,95+,103-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,150-,151-,152-,153-,154-/m0/s1

InChIKey=MKODHBXHXSGJDK-JQJCOVQTSA-N


Database reference: