BIOPEP-UWM: Report

ID 3150
Name erythropoietin receptor agonist peptide
sequence
DREGCRRGWVGQCKAWFN
Function:
Erythropoietin receptor agonist
 
Number of residues
18
Activity code
sti
Activity :
stimulating
Chemical mass 2168.4169 Monoisotopic mass 2166.9923
EC50 :
0.04 µM


Bibliographic data:
Authors
McConnell S. J., Dinh T., Le M-H., Brown S. J., Becherer K. et al.
Title
Isolation of erythropoietin receptor agonist peptides using evolved phage libraries. Biol. Chem., 379, 1279-1286 (1998)
Year Source
1998 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(CC(O)=O)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)NCC(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)NCC(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CC(N)=O)C(O)=O

InChI=1S/C93H138N32O25S2/c1-46(2)75(89(148)111-43-70(128)113-61(26-28-68(96)126)83(142)124-67(45-152)88(147)118-57(22-11-12-30-94)80(139)112-47(3)76(135)121-64(36-50-40-108-55-21-10-8-19-52(50)55)85(144)122-62(34-48-16-5-4-6-17-48)84(143)123-65(90(149)150)38-69(97)127)125-86(145)63(35-49-39-107-54-20-9-7-18-51(49)54)114-71(129)41-109-78(137)56(23-13-31-104-91(98)99)117-82(141)59(25-15-33-106-93(102)103)119-87(146)66(44-151)115-72(130)42-110-79(138)60(27-29-73(131)132)120-81(140)58(24-14-32-105-92(100)101)116-77(136)53(95)37-74(133)134/h4-10,16-21,39-40,46-47,53,56-67,75,107-108,151-152H,11-15,22-38,41-45,94-95H2,1-3H3,(H2,96,126)(H2,97,127)(H,109,137)(H,110,138)(H,111,148)(H,112,139)(H,113,128)(H,114,129)(H,115,130)(H,116,136)(H,117,141)(H,118,147)(H,119,146)(H,120,140)(H,121,135)(H,122,144)(H,123,143)(H,124,142)(H,125,145)(H,131,132)(H,133,134)(H,149,150)(H4,98,99,104)(H4,100,101,105)(H4,102,103,106)/t47-,53-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,75-/m0/s1

InChIKey=ISUYXWOZMMMXDP-UTPFKUSOSA-N


Database reference: