BIOPEP-UWM: Report

ID 3151
Name erythropoietin receptor agonist peptide
sequence
REGCRRGWVGQCKAWFN
Function:
Erythropoietin receptor agonist
 
Number of residues
17
Activity code
sti
Activity :
stimulating
Chemical mass 2053.3297 Monoisotopic mass 2051.9655
EC50 :
0.09 µM


Bibliographic data:
Authors
McConnell S. J., Dinh T., Le M-H., Brown S. J., Becherer K. et al.
Title
Isolation of erythropoietin receptor agonist peptides using evolved phage libraries. Biol. Chem., 379, 1279-1286 (1998)
Year Source
1998 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(CCCNC(N)=N)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)NCC(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)NCC(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CC(N)=O)C(O)=O

InChI=1S/C89H133N31O22S2/c1-45(2)72(85(140)107-42-68(123)109-59(26-28-66(92)121)79(134)119-65(44-144)84(139)114-56(23-11-12-30-90)77(132)108-46(3)73(128)116-62(36-49-39-104-54-22-10-8-19-51(49)54)81(136)117-60(34-47-16-5-4-6-17-47)80(135)118-63(86(141)142)37-67(93)122)120-82(137)61(35-48-38-103-53-21-9-7-18-50(48)53)110-69(124)40-105-75(130)55(24-14-32-101-88(96)97)113-78(133)57(25-15-33-102-89(98)99)115-83(138)64(43-143)111-70(125)41-106-76(131)58(27-29-71(126)127)112-74(129)52(91)20-13-31-100-87(94)95/h4-10,16-19,21-22,38-39,45-46,52,55-65,72,103-104,143-144H,11-15,20,23-37,40-44,90-91H2,1-3H3,(H2,92,121)(H2,93,122)(H,105,130)(H,106,131)(H,107,140)(H,108,132)(H,109,123)(H,110,124)(H,111,125)(H,112,129)(H,113,133)(H,114,139)(H,115,138)(H,116,128)(H,117,136)(H,118,135)(H,119,134)(H,120,137)(H,126,127)(H,141,142)(H4,94,95,100)(H4,96,97,101)(H4,98,99,102)/t46-,52-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,72-/m0/s1

InChIKey=GCFKLVAGSUCBSO-JJTLWQKHSA-N


Database reference: