BIOPEP-UWM: Report

ID 3152
Name erythropoietin receptor agonist peptide
sequence
EGCRRGWVGQCKAWFN
Function:
Erythropoietin receptor agonist
 
Number of residues
16
Activity code
sti
Activity :
stimulating
Chemical mass 1897.1445 Monoisotopic mass 1895.8646
EC50 :
3.70 µM


Bibliographic data:
Authors
McConnell S. J., Dinh T., Le M-H., Brown S. J., Becherer K. et al.
Title
Isolation of erythropoietin receptor agonist peptides using evolved phage libraries. Biol. Chem., 379, 1279-1286 (1998)
Year Source
1998 Journal


Additional information:

BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(CCC(O)=O)C(=O)NCC(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)NCC(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CC(N)=O)C(O)=O

InChI=1S/C83H121N27O21S2/c1-42(2)68(110-77(126)57(32-45-35-94-50-19-9-7-17-47(45)50)101-65(114)38-97-71(120)52(22-13-29-92-82(88)89)103-73(122)54(23-14-30-93-83(90)91)105-78(127)60(40-132)102-66(115)37-96-70(119)49(85)24-27-67(116)117)80(129)98-39-64(113)100-55(25-26-62(86)111)74(123)109-61(41-133)79(128)104-53(21-11-12-28-84)72(121)99-43(3)69(118)106-58(33-46-36-95-51-20-10-8-18-48(46)51)76(125)107-56(31-44-15-5-4-6-16-44)75(124)108-59(81(130)131)34-63(87)112/h4-10,15-20,35-36,42-43,49,52-61,68,94-95,132-133H,11-14,21-34,37-41,84-85H2,1-3H3,(H2,86,111)(H2,87,112)(H,96,119)(H,97,120)(H,98,129)(H,99,121)(H,100,113)(H,101,114)(H,102,115)(H,103,122)(H,104,128)(H,105,127)(H,106,118)(H,107,125)(H,108,124)(H,109,123)(H,110,126)(H,116,117)(H,130,131)(H4,88,89,92)(H4,90,91,93)/t43-,49-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,68-/m0/s1

InChIKey=BLGXDMYGGDVZQN-AVEJGSETSA-N


Database reference: