BIOPEP-UWM: Report

ID 3153
Name erythropoietin receptor agonist peptide
sequence
DVEACGGGWVGHCNYWLRDEYASKPIKQVPPGNHNQPS
Function:
Erythropoietin receptor agonist
 
Number of residues
38
Activity code
sti
Activity :
stimulating
Chemical mass 4210.5729 Monoisotopic mass 4207.9320
EC50 :
0.00 µM


Bibliographic data:
Authors
McConnell S. J., Dinh T., Le M-H., Brown S. J., Becherer K. et al.
Title
Isolation of erythropoietin receptor agonist peptides using evolved phage libraries. Biol. Chem., 379, 1279-1286 (1998)
Year Source
1998 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(CC(O)=O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CS)C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CC1=CN=CN1)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCCCN)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(C(C)C)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(=O)NCC(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CC1=CN=CN1)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CO)C(O)=O

InChI=1S/C185H270N54O56S2/c1-13-92(10)151(179(289)216-108(31-18-20-54-186)157(267)214-110(46-50-134(189)244)160(270)234-150(91(8)9)183(293)239-60-26-37-133(239)182(292)238-59-23-34-130(238)174(284)204-80-142(252)212-122(69-136(191)246)167(277)224-121(67-100-76-197-87-207-100)166(276)225-123(70-137(192)247)168(278)219-114(47-51-135(190)245)181(291)236-57-24-35-131(236)175(285)229-127(83-241)184(294)295)235-176(286)132-36-25-58-237(132)180(290)113(32-19-21-55-187)218-172(282)126(82-240)228-152(262)93(11)209-161(271)116(62-95-38-42-101(242)43-39-95)221-159(269)112(49-53-145(256)257)215-170(280)125(72-147(260)261)227-158(268)109(33-22-56-198-185(194)195)213-162(272)115(61-88(2)3)220-164(274)119(65-98-74-200-107-30-17-15-28-104(98)107)223-163(273)117(63-96-40-44-102(243)45-41-96)222-169(279)124(71-138(193)248)226-173(283)129(85-297)231-165(275)120(66-99-75-196-86-206-99)211-143(253)81-205-177(287)148(89(4)5)233-171(281)118(64-97-73-199-106-29-16-14-27-103(97)106)210-141(251)79-202-139(249)77-201-140(250)78-203-155(265)128(84-296)230-153(263)94(12)208-156(266)111(48-52-144(254)255)217-178(288)149(90(6)7)232-154(264)105(188)68-146(258)259/h14-17,27-30,38-45,73-76,86-94,105,108-133,148-151,199-200,240-243,296-297H,13,18-26,31-37,46-72,77-85,186-188H2,1-12H3,(H2,189,244)(H2,190,245)(H2,191,246)(H2,192,247)(H2,193,248)(H,196,206)(H,197,207)(H,201,250)(H,202,249)(H,203,265)(H,204,284)(H,205,287)(H,208,266)(H,209,271)(H,210,251)(H,211,253)(H,212,252)(H,213,272)(H,214,267)(H,215,280)(H,216,289)(H,217,288)(H,218,282)(H,219,278)(H,220,274)(H,221,269)(H,222,279)(H,223,273)(H,224,277)(H,225,276)(H,226,283)(H,227,268)(H,228,262)(H,229,285)(H,230,263)(H,231,275)(H,232,264)(H,233,281)(H,234,270)(H,235,286)(H,254,255)(H,256,257)(H,258,259)(H,260,261)(H,294,295)(H4,194,195,198)/t92-,93-,94-,105-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,148-,149-,150-,151-/m0/s1

InChIKey=NZXFMTQIBXAWGU-PKCJKTGDSA-N


Database reference: