BIOPEP-UWM: Report

ID 3155
Name erythropoietin receptor agonist peptide
sequence
LLQMCSPGWVGHCNDWPRDEYANNPPNPVVDRQALTPP
Function:
Erythropoietin receptor agonist
 
Number of residues
38
Activity code
sti
Activity :
stimulating
Chemical mass 4288.7501 Monoisotopic mass 4285.9821
EC50 :
0.00 µM


Bibliographic data:
Authors
McConnell S. J., Dinh T., Le M-H., Brown S. J., Becherer K. et al.
Title
Isolation of erythropoietin receptor agonist peptides using evolved phage libraries. Biol. Chem., 379, 1279-1286 (1998)
Year Source
1998 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CO)C(=O)N1CCC[C@@]1([H])C(=O)NCC(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CC1=CN=CN1)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CC(N)=O)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(O)=O

InChI=1S/C188H280N54O56S3/c1-87(2)64-103(189)153(264)220-112(65-88(3)4)161(272)214-109(48-51-136(191)247)157(268)216-111(53-63-301-16)159(270)230-127(85-300)171(282)229-125(83-243)182(293)236-56-23-36-128(236)172(283)205-81-141(252)210-115(68-97-78-203-104-32-19-17-30-101(97)104)169(280)232-147(90(7)8)176(287)206-82-142(253)211-116(70-99-80-200-86-207-99)162(273)231-126(84-299)170(281)222-118(72-138(193)249)163(274)224-120(76-145(258)259)167(278)226-122(69-98-79-204-105-33-20-18-31-102(98)105)179(290)237-57-24-37-129(237)173(284)217-107(35-22-55-202-188(198)199)156(267)223-119(75-144(256)257)165(276)215-110(49-52-143(254)255)158(269)221-114(67-96-43-45-100(245)46-44-96)160(271)209-94(14)152(263)219-117(71-137(192)248)164(275)227-123(73-139(194)250)181(292)240-60-27-40-132(240)183(294)239-59-26-38-130(239)174(285)228-124(74-140(195)251)180(291)238-58-25-39-131(238)175(286)233-149(92(11)12)178(289)234-148(91(9)10)177(288)225-121(77-146(260)261)166(277)212-106(34-21-54-201-187(196)197)155(266)213-108(47-50-135(190)246)154(265)208-93(13)151(262)218-113(66-89(5)6)168(279)235-150(95(15)244)185(296)241-61-28-41-133(241)184(295)242-62-29-42-134(242)186(297)298/h17-20,30-33,43-46,78-80,86-95,103,106-134,147-150,203-204,243-245,299-300H,21-29,34-42,47-77,81-85,189H2,1-16H3,(H2,190,246)(H2,191,247)(H2,192,248)(H2,193,249)(H2,194,250)(H2,195,251)(H,200,207)(H,205,283)(H,206,287)(H,208,265)(H,209,271)(H,210,252)(H,211,253)(H,212,277)(H,213,266)(H,214,272)(H,215,276)(H,216,268)(H,217,284)(H,218,262)(H,219,263)(H,220,264)(H,221,269)(H,222,281)(H,223,267)(H,224,274)(H,225,288)(H,226,278)(H,227,275)(H,228,285)(H,229,282)(H,230,270)(H,231,273)(H,232,280)(H,233,286)(H,234,289)(H,235,279)(H,254,255)(H,256,257)(H,258,259)(H,260,261)(H,297,298)(H4,196,197,201)(H4,198,199,202)/t93-,94-,95+,103-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,147-,148-,149-,150-/m0/s1

InChIKey=GHKDOUWHDMZOQJ-ZEKRIZOVSA-N


Database reference: