BIOPEP-UWM: Report

ID 3156
Name erythropoietin receptor agonist peptide
sequence
DFEDCQGGWVGHCNDWLGDEYARHPRYGATQTLSVNRH
Function:
Erythropoietin receptor agonist
 
Number of residues
38
Activity code
sti
Activity :
stimulating
Chemical mass 4391.6389 Monoisotopic mass 4388.9193
EC50 :
0.00 µM


Bibliographic data:
Authors
McConnell S. J., Dinh T., Le M-H., Brown S. J., Becherer K. et al.
Title
Isolation of erythropoietin receptor agonist peptides using evolved phage libraries. Biol. Chem., 379, 1279-1286 (1998)
Year Source
1998 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(CC(O)=O)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)NCC(=O)NCC(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CC1=CN=CN1)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CC1=CN=CN1)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CC1=CN=CN1)C(O)=O

InChI=1S/C189H269N59O60S2/c1-86(2)54-116(230-169(290)122(60-98-71-208-108-29-19-17-27-105(98)108)233-174(295)127(68-148(271)272)236-172(293)124(65-137(193)256)234-179(300)133(82-310)242-170(291)123(61-99-72-201-83-214-99)220-143(262)79-213-181(302)150(88(5)6)244-176(297)121(59-97-70-207-107-28-18-16-26-104(97)107)219-141(260)76-209-139(258)75-210-157(278)112(42-46-135(191)254)224-178(299)132(81-309)243-175(296)128(69-149(273)274)235-164(285)115(45-49-145(265)266)225-168(289)120(56-94-24-14-13-15-25-94)229-156(277)106(190)64-146(267)268)158(279)212-78-142(261)221-126(67-147(269)270)173(294)226-114(44-48-144(263)264)163(284)232-119(58-96-36-40-103(253)41-37-96)166(287)218-91(10)154(275)222-109(30-20-50-204-187(195)196)161(282)239-129(62-100-73-202-84-215-100)185(306)248-53-23-33-134(248)180(301)227-111(32-22-52-206-189(199)200)160(281)231-118(57-95-34-38-102(252)39-35-95)159(280)211-77-140(259)217-90(9)155(276)246-152(92(11)250)183(304)228-113(43-47-136(192)255)165(286)247-153(93(12)251)184(305)237-117(55-87(3)4)167(288)241-131(80-249)177(298)245-151(89(7)8)182(303)238-125(66-138(194)257)171(292)223-110(31-21-51-205-188(197)198)162(283)240-130(186(307)308)63-101-74-203-85-216-101/h13-19,24-29,34-41,70-74,83-93,106,109-134,150-153,207-208,249-253,309-310H,20-23,30-33,42-69,75-82,190H2,1-12H3,(H2,191,254)(H2,192,255)(H2,193,256)(H2,194,257)(H,201,214)(H,202,215)(H,203,216)(H,209,258)(H,210,278)(H,211,280)(H,212,279)(H,213,302)(H,217,259)(H,218,287)(H,219,260)(H,220,262)(H,221,261)(H,222,275)(H,223,292)(H,224,299)(H,225,289)(H,226,294)(H,227,301)(H,228,304)(H,229,277)(H,230,290)(H,231,281)(H,232,284)(H,233,295)(H,234,300)(H,235,285)(H,236,293)(H,237,305)(H,238,303)(H,239,282)(H,240,283)(H,241,288)(H,242,291)(H,243,296)(H,244,297)(H,245,298)(H,246,276)(H,247,286)(H,263,264)(H,265,266)(H,267,268)(H,269,270)(H,271,272)(H,273,274)(H,307,308)(H4,195,196,204)(H4,197,198,205)(H4,199,200,206)/t90-,91-,92+,93+,106-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,150-,151-,152-,153-/m0/s1

InChIKey=OYVWFBZJLRFUJA-AZBQLCIQSA-N


Database reference: