BIOPEP-UWM: Report

ID 3159
Name erythropoietin receptor agonist peptide
sequence
AKVVCRNGWVGHCSAWLTDEYESNPNTRIPNTFDMKTP
Function:
Erythropoietin receptor agonist
 
Number of residues
38
Activity code
sti
Activity :
stimulating
Chemical mass 4338.8070 Monoisotopic mass 4336.0187
EC50 :
0.00 µM


Bibliographic data:
Authors
McConnell S. J., Dinh T., Le M-H., Brown S. J., Becherer K. et al.
Title
Isolation of erythropoietin receptor agonist peptides using evolved phage libraries. Biol. Chem., 379, 1279-1286 (1998)
Year Source
1998 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@@](C)(N)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CC(N)=O)C(=O)NCC(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CC1=CN=CN1)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC1=CNC2=C1C=CC=C2)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N1CCC[C@@]1([H])C(O)=O

InChI=1S/C189H286N54O58S3/c1-18-91(10)147(185(298)242-62-33-46-132(242)177(290)225-123(73-136(195)253)171(284)239-149(95(14)247)182(295)226-117(66-98-35-20-19-21-36-98)163(276)223-124(75-142(261)262)166(279)217-114(56-64-304-17)158(271)213-109(42-27-29-58-191)161(274)240-151(97(16)249)186(299)243-63-34-47-133(243)187(300)301)236-160(273)111(44-31-60-203-189(199)200)218-181(294)148(94(13)246)238-170(283)122(72-135(194)252)224-176(289)131-45-32-61-241(131)184(297)126(74-137(196)254)228-173(286)128(83-245)229-157(270)113(53-55-141(259)260)215-162(275)116(67-99-48-50-103(250)51-49-99)221-156(269)112(52-54-140(257)258)216-167(280)125(76-143(263)264)227-183(296)150(96(15)248)237-168(281)115(65-87(2)3)220-164(277)119(69-101-78-205-107-40-25-23-38-105(101)107)219-153(266)93(12)209-172(285)127(82-244)230-175(288)129(84-302)231-165(278)120(70-102-79-201-86-208-102)211-139(256)81-207-178(291)144(88(4)5)233-169(282)118(68-100-77-204-106-39-24-22-37-104(100)106)210-138(255)80-206-154(267)121(71-134(193)251)222-155(268)110(43-30-59-202-188(197)198)214-174(287)130(85-303)232-179(292)145(89(6)7)235-180(293)146(90(8)9)234-159(272)108(41-26-28-57-190)212-152(265)92(11)192/h19-25,35-40,48-51,77-79,86-97,108-133,144-151,204-205,244-250,302-303H,18,26-34,41-47,52-76,80-85,190-192H2,1-17H3,(H2,193,251)(H2,194,252)(H2,195,253)(H2,196,254)(H,201,208)(H,206,267)(H,207,291)(H,209,285)(H,210,255)(H,211,256)(H,212,265)(H,213,271)(H,214,287)(H,215,275)(H,216,280)(H,217,279)(H,218,294)(H,219,266)(H,220,277)(H,221,269)(H,222,268)(H,223,276)(H,224,289)(H,225,290)(H,226,295)(H,227,296)(H,228,286)(H,229,270)(H,230,288)(H,231,278)(H,232,292)(H,233,282)(H,234,272)(H,235,293)(H,236,273)(H,237,281)(H,238,283)(H,239,284)(H,240,274)(H,257,258)(H,259,260)(H,261,262)(H,263,264)(H,300,301)(H4,197,198,202)(H4,199,200,203)/t91-,92-,93-,94+,95+,96+,97+,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,144-,145-,146-,147-,148-,149-,150-,151-/m0/s1

InChIKey=VBXIYYTXCANAQM-BRFMTJCHSA-N


Database reference: