BIOPEP-UWM: Report

ID 3169
Name dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
GP
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
2
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 172.1813 Monoisotopic mass 172.0845
EC50 :
9690.00 µM


Bibliographic data:
Authors
Gallego M., Aristoy M.-C., Toldrá F.
Title
Post-proline cleaving enzyme and post-proline dipeptidyl aminopeptidase: comparison of two peptidases with high specificity for proline residues. J. Biol. Chem., 253, 3708-3716, 1978
Year Source
2014 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: C1C[C@H](N(C1)C(=O)CN)C(=O)O

InChI=1S/C7H12N2O3/c8-4-6(10)9-3-1-2-5(9)7(11)12/h5H,1-4,8H2,(H,11,12)/t5-/m0/s1

InChIKey: KZNQNBZMBZJQJO-YFKPBYRVSA-N


Information concerning Dipeptidyl Peptidase IV (synonym: Dipeptidyl Aminopeptidase IV) (EC 3.4.14.5) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: S09.003


Inhibitor of angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 7512), the ChEMBL database, the EROP-Moscow database (ID E09223), the MBPDB database; the PubChem database
Antithrombotic peptide according to the BIOPEP-UWM database of bioactive peptides (ID 3283);
Inhibitor of prolyl endopeptidase (EC 3.4.21.26) (MEROPS ID: S09.001) according to the BIOPEP-UWM database of bioactive peptides (ID 3461)
Regulator of the stomach mucosal membrane activity according to the BIOPEP-UWM database of bioactive peptides (ID 2753)

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids, the ChEMBL database; the EROP-Moscow database (ID E03695), the PubChem database

InChI=1S/C7H12N2O3/c8-4-6(10)9-3-1-2-5(9)7(11)12/h5H,1-4,8H2,(H,11,12)/t5-/m0/s1

InChIKey: KZNQNBZMBZJQJO-YFKPBYRVSA-N


Information concerning Dipeptidyl Peptidase IV (synonym: Dipeptidyl Aminopeptidase IV) (EC 3.4.14.5) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: S09.003


Inhibitor of angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: XM02-001) according to AHTPDB database; BIOPEP database of bioactive peptides (ID 7512), EROP-Moscow database (ID E09223)
Antithrombotic peptide according to BIOPEP database of bioactive peptides (ID 3283);
Inhibitor of prolyl endopeptidase (EC 3.4.21.26) (MEROPS ID: S09.001) according to BIOPEP database of bioactive peptides (ID 3461)
Regulator of the stomach mucosal membrane activity according to BIOPEP database of bioactive peptides (ID 2753)

Bitter peptide according to BIOPEP database of sensory peptides and amino acids, EROP-Moscow database (ID E03695).


Database reference:
AHTPDB: ID 1391; 1392; 1420; 3413; 3489; 3614; 3795; 3840; 3930; 4434; 4501; 4694; 5151; 5426; 5642; 5677; 6111; 6163; 6522

BindingDB: ID 50169189

BioCyc: ID CPD-10814

BioPepDB: ID biopep00379

BIOPEP-UWM database of bioactive peptides ID: 2753; 3283; 3461; 7512

BIOPEP-UWM database of sensory peptides and amino acids: ID 17

BRENDA: Ligand Gly-Pro

ChEBI: ID 70744

ChEMBL: ID CHEMBL80548

ChemSpider: ID 2282246

EROP-Moscow: ID E03695; E09223

FDA SRS: ID BJZ69WB3VD

J-GLOBAL: ID 200907097129168220

MBPDB: Peptide GP

Metabolights: ID MTBLC70744

Nikkaji: ID J150.128C

PubChem: ID 3013625

Rhea: ID 73779

SATPdb: ID satpdb20549

SureChEMBL: ID SCHEMBL155067

ZINC: ID ZINC01637972