BIOPEP-UWM: Report

ID 3170
Name dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
PP
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
2
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 212.2450 Monoisotopic mass 212.1157
IC50 :
5860.00 µM


Bibliographic data:
Authors
Hatanaka T., Inoue Y., Arima J., Kumagai Y., Usuki H., Kawakami K., Kimura M., Mukaihara T.
Title
Production of dipeptidyl peptidase IV inhibitory peptides from defated rice bran. Food Chem., 134, 797-802
Year Source
2012 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: C1C[C@@H](C(=O)N2CCC[C@H]2C(=O)O)NC1

InChI=1S/C10H16N2O3/c13-9(7-3-1-5-11-7)12-6-2-4-8(12)10(14)15/h7-8,11H,1-6H2,(H,14,15)/t7-,8-/m0/s1

InChIKey: RWCOTTLHDJWHRS-YUMQZZPRSA-N


First reference concerning peptide:
Yoshimoto T., Fischl M., Orlowski R. C., Walter R., 1978, Post-proline cleaving enzyme and post-proline dipeptidyl aminopeptidase: comparison of two peptidases with high specificity for proline residues. J. Biol. Chem., 253, 3708-3716

Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database, the BIOPEP-UWM database of bioactive peptides (ID 7836); the EROP-Moscow database (ID E01865)
Inhibitor of alpha-glucosidase (EC 3.2.1.20) according to the BIOPEP-UWM database of bioactive peptides (ID 9651)

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids.


Database reference:
AHTPDB: ID 3007; 3289; 3445; 3527; 3579; 4007; 5442; 6739

BindingDB: ID 50169141

BioPepDB: ID biopep01074

BIOPEP-UWM database of bioactive peptides: ID 7836; 9651

BIOPEP-UWM database of sensory peptides and amino acids: ID 5

BRENDA: Ligand Pro-Pro

CHEBI: ID 73646

ChEMBL: ID CHEMBL371194

ChemSpider: ID 9797341

EROP-Moscow: ID E01865; E09232

HMDB: ID HMDB0011180

J-GLOBAL: ID 200907033363473135

Metabolights: ID MTBLC73646

Nikkaji: ID J364.500B

NIST: ID 20488-28-2

PubChem: CID 11622593

SATPdb: ID satpdb13817

ZINC: ID ZINC04899613