BIOPEP-UWM: Report

ID 3174
Name dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
KA
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
2
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 217.2647 Monoisotopic mass 217.1422
IC50 :
6270.00 µM


Bibliographic data:
Authors
Gallego M., Aristoy M.-C., Toldrá F.
Title
Dipeptidyl peptidase IV inhibitory peptides generated in Spanish dry-cured ham. Meat Science, 96, 757-761, 2014
Year Source
2014 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)O

InChI=1S/C9H19N3O3/c1-6(9(14)15)12-8(13)7(11)4-2-3-5-10/h6-7H,2-5,10-11H2,1H3,(H,12,13)(H,14,15)/t6-,7-/m0/s1

InChIKey: QOOWRKBDDXQRHC-BQBZGAKWSA-N


First note concerning peptide:

Bella A. M., Erickson R. H. Jr., Kim Y. S. Rat intestinal brush border membrane dipeptidyl-aminopeptidase IV:kinetic properties and substrate specifities of the purified enzyme. Arch. Biochem. Biophys. 218 (1), 156-162 (1982)


Inhibitor of angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BindingDB database, the BIOPEP-UWM database of bioactive peptides (ID 7743), the BRENDA database, the ChEMBL database, the EROP-Moscow database; the PubChem database
Inhibitor of Leucyltranferase (EC 2.3.2.6) according to the BRENDA database
Inhibitor of the bleomycin hydrolase (EC 3.4.22.40) according to the BRENDA database
Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BIOPEP-UWM database of bioactive peptides (ID 9511)


Database reference:
AHTPDB: ID 1700, 2991, 3029, 3052, 3067, 3170, 3174, 3275, 3321, 3435, 3505, 3829, 3964, 4436, 4535, 4675, 5157, 6113, 6691

BindingDB: ID 50169138

BioPepDB: ID biopep00660

BIOPEP-UWM database of bioactive peptides: ID 7743; 9511

BRENDA: Ligand Lys-Ala

ChEBI: ID 61872

ChEMBL: ID CHEMBL93178

ChemSpider: ID 5374071

EPA CompTox: ID DTXSID20426662

EPA DSSTox: ID DTXCID50377496

EROP-Moscow: ID E09228; E14731

FeptideDB: ID 3174; 7743

FooDB: ID FDB111967

HMDB: ID HMDB0028944

J-GLOBAL: ID 200907026921821335

Nikkaji: ID J82.576J

PlantPepDB: ID PPepDB_2919

PubChem: CID 7010504

SATPdb: ID satpdb16222

SureChEMBL: ID SCHEMBL1641741

ZINC: ID ZINC000002390920